Protein Alignment Pph13 and pitx2

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001017227.1
• Gene: pitx2 / 549981
• XenbaseID: XB-GENE-482492
• Length: 345
• Species: Xenopus tropicalis
• Alignment Length: 228
• Identity: 74/228 - (32%)
• Similarity: 108/228 - (47%)
• Gaps: 40/228 - (17%)

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66
            |..:.|::|||.||.|.:.||||||..|||..|||:..|||:||..:||||||:|||:|||||||
 Frog   105 DDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 169

  Fly    67 KQEK--------------IGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLP-----DT 112
            |:|:              ..||...|.:  :....||::.|..|...::|....  .|     :.
 Frog   170 KRERNQQAELCKNGFGPQFNGLMQPYDD--MYPSYSYNNWAAKGLTSASLSTKS--FPFFNSMNV 230

  Fly   113 PPQSSNSL---DNELKASYGTGAMSPSRLS--PNIFLNL--NIDHLGLERGGSGLSMEWSTYPPQ 170
            .|.||.|:   .|.:.:...:..|.||.::  |...||.  |:::|......:.:......|.|.
 Frog   231 NPLSSQSMFSSPNSISSMSMSSGMVPSAVTGVPGSGLNSLNNLNNLSNPSLNTAVPTSACPYAPP 295

  Fly   171 TQAQTHPQMDSDN--------QLQQHPPQQHAS 195
            |....:  .|:.|        :.:||....:||
 Frog   296 TPPYVY--RDTCNSSLASLRLKAKQHSSFGYAS 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	37/55 (67%)
pitx2	NP_001017227.1	Homeodomain	114..170	CDD:459649	37/55 (67%)
		OAR	303..320	CDD:461067	3/16 (19%)