DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pph13 and toe

DIOPT Version :9

Sequence 1:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_524041.2	Gene:	toe / 39418	FlyBaseID:	FBgn0036285	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	272	Identity:	74/272 - (27%)
Similarity:	106/272 - (38%)	Gaps:	80/272 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGG 73
            |.||.||||:..||.|||:.|.::|||.|..||:||.|..|:||||||||.|||||||:.:::..
  Fly   383 KFRRNRTTFSPEQLDELEKEFDKSHYPCVNTREKLAARTALSEARVQVWFSNRRAKWRRHQRVNL 447

  Fly    74 L------------------------------------GGDYKEGALDLDVSYDDSAVLGQLDSA- 101
            :                                    .|..|:     ...|..|.:.....|:
  Fly   448 IKQRDSPSTSSSPTPLVNPVVSPVSPIPVPVPVAVPESGQQKQ-----PYPYSTSNMCNTSSSSS 507

  Fly   102 -------LGGGGTLLPDTPPQSSNSLDNELKASYGTGAMSPSRLSPNIFLNLNIDHLGLERGGS- 158
                   :..|..:...|...|||....|..|:..|.  ||:..:|            |..||.
  Fly   508 NSQPCNTINPGSKMSSKTSSVSSNQHMEEPAAAVATA--SPTASAP------------LSMGGEN 558

  Fly   159 ----GLSMEWSTYP-PQTQAQTHPQMDSDNQLQQHPPQQ--------HASDPIHAGSSSHHQQQQ 210
                .|.|   |.| |.|.........:.:..:|:..:.        |.|.||.|.|...||.::
  Fly   559 SAFRALPM---TLPMPMTLPTASAAAFALSFARQYIAKYMGTPLNLGHGSSPIQAQSGRDHQSEE 620

  Fly   211 QQHQQEQHNPQL 222
            ::::.||...::
  Fly   621 REYEDEQEEEEV 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	33/51 (65%)
toe	NP_524041.2	HTH	134..230	CDD:304362
toe	NP_524041.2	Homeobox	388..440	CDD:278475	33/51 (65%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450821
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840