Protein Alignment Pph13 and HOXB3

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_016880049.1
• Gene: HOXB3 / 3213
• HGNCID: 5114
• Length: 578
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 66/262 - (25%)
• Similarity: 101/262 - (38%)
• Gaps: 72/262 - (27%)

  Fly    11 RRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGGL- 74
            :|.||.:.:.||.|||:.|....|.....|.|:|..::|:|.::::||||||.|::|.:|..||
Human   336 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLA 400

  Fly    75 ---GGDYKEG--------------AL-DLDVSYDDS-------------AVLGQLDSALGGGGT- 107
               ||....|              || .:..||:..             |:.......|.|.|.
Human   401 SSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAP 465

  Fly   108 -LLPDTP-PQSSNSLDNELKASYGTGAMS---------------PSRLSPNIFLNLNIDHLGLER 155
             ..|.|| |:....:......:|||..|.               |....|:::   .::||....
Human   466 QKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLY---GLNHLSHHP 527

  Fly   156 GGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHASDPIHAGSSSHHQQQQQQHQQEQHNP 220
            .|   :::::..||...:|.|           .|.:.|   |.:...||||....|...||.  |
Human   528 SG---NLDYNGAPPMAPSQHH-----------GPCEPH---PTYTDLSSHHAPPPQGRIQEA--P 573

  Fly   221 QL 222
            :|
Human   574 KL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	22/55 (40%)
HOXB3	XP_016880049.1	Homeodomain	336..392	CDD:459649	22/55 (40%)
		DUF4074	513..576	CDD:463833	20/85 (24%)