Protein Alignment Pph13 and pitx2

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_571050.1
• Gene: pitx2 / 30164
• ZFINID: ZDB-GENE-990714-27
• Length: 314
• Species: Danio rerio
• Alignment Length: 233
• Identity: 75/233 - (32%)
• Similarity: 107/233 - (45%)
• Gaps: 50/233 - (21%)

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66
            |..:.|::|||.||.|.:.||||||..|||..|||:..|||:||..:||||||:|||:|||||||
Zfish    74 DDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 138

  Fly    67 KQEK--------------IGGLGGDYKEGALDLDVSYDDSAVLGQLDSALG-------------- 103
            |:|:              ..||...|.:  :....:|::.|..|...::|.
Zfish   139 KRERNQQAELCKNGFGPQFNGLMQPYDD--MYPSYTYNNWAAKGLTSASLSTKSFPFFNSMNVNP 201

  Fly   104 -GGGTLLPDTPPQ--SSNSLDNELKASYGTGAMSPSRLSPNIFLNLNIDHLGLERGGSGLSMEWS 165
             ...|:.  :||.  ||.|:.:.:..|..||....|..|.|     |:::|......||:.....
Zfish   202 LSSQTMF--SPPNSISSMSMSSSMVPSAVTGVPGSSLNSLN-----NLNNLSNPSLNSGVPTPAC 259

  Fly   166 TYPPQTQAQTHPQMDSDN--------QLQQHPPQQHAS 195
            .|.|.|....:  .|:.|        :.:||....:||
Zfish   260 PYAPPTPPYVY--RDTCNSSLASLRLKAKQHSSFGYAS 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	37/55 (67%)
pitx2	NP_571050.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		8/18 (44%)
		Homeodomain	83..139	CDD:459649	37/55 (67%)
		OAR	272..289	CDD:461067	3/16 (19%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	276..289		1/12 (8%)
		Nuclear localization signal. /evidence=ECO:0000255	282..286		0/3 (0%)