Protein Alignment Pph13 and OTP

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_115485.1
• Gene: OTP / 23440
• HGNCID: 8518
• Length: 325
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 75/212 - (35%)
• Similarity: 97/212 - (45%)
• Gaps: 57/212 - (26%)

  Fly     7 KRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEK- 70
            ::||:|:||.|...||.||||:|.:|||||:|.|||||:||.|||:|||||||||||||:|::|
Human   101 QQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKT 165

  Fly    71 ------------IGGLGGDYKEGALDLDVSYDDS--------------AVLG----QLDSALGGG 105
                        ..|| ..:...|.....:..||              |:.|    .|..|||..
Human   166 TNVFRAPGTLLPTPGL-PQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQ 229

  Fly   106 GTL--------LPDTPPQSSNSLDNELKASYGTGAMS-----------------PSRLSPNIFLN 145
            ..:        |...||.:|..|.|.|..|.|.|..|                 ||.:|.:..|.
Human   230 QAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLC 294

  Fly   146 LNIDHLGLERGGSGLSM 162
            .:.|...:.||.|..|:
Human   295 SSPDSSDVWRGTSIASL 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	40/55 (73%)
OTP	NP_115485.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..112		5/10 (50%)
		Homeodomain	106..156	CDD:459649	35/49 (71%)
		OAR	303..320	CDD:461067	4/9 (44%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319		2/6 (33%)