DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pph13 and Rax

DIOPT Version :9

Sequence 1:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_038861.2	Gene:	Rax / 19434	MGIID:	109632	Length:	342	Species:	Mus musculus

Alignment Length:	195	Identity:	72/195 - (36%)
Similarity:	96/195 - (49%)	Gaps:	28/195 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKI 71
            |:|.||.||||.|.||.||||||:::|||||:.|||||.:::|.|.||||||||||||||:|||:
Mouse   133 KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKL 197

  Fly    72 GGLGGDYKEGALDLDVSYD---DSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAM 133
            .......::..|   :|:.   .|:.|..|.:..|.|     ..||.|:..|:..|......|..
Mouse   198 EVSSMKLQDSPL---LSFSRSPPSSALAPLGTGPGSG-----SGPPGSALPLEPWLGPPLPGGGA 254

  Fly   134 SPSRLSPNIFLNLNIDHLGLERGGSGLSMEWSTYPP-QTQAQTHPQMDSDNQLQQHPPQQHASDP 197
            :..:..|           |....|.||...::..|| ...|...|.:.     |..||..:...|
Mouse   255 TALQSLP-----------GFGPPGQGLPASYTPPPPFLNSAPLGPGLQ-----QLGPPPAYPCAP 303

Fly 198 197
Mouse 304 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	37/51 (73%)
Rax	NP_038861.2	Octapeptide motif	33..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..140		4/6 (67%)
		Homeobox	140..192	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	208..295		23/110 (21%)
		OAR	316..331	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	319..332
		Nuclear localization signal. /evidence=ECO:0000255	325..329
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920