Protein Alignment Pph13 and Pitx2

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001035967.1
• Gene: Pitx2 / 18741
• MGIID: 109340
• Length: 324
• Species: Mus musculus
• Alignment Length: 241
• Identity: 77/241 - (31%)
• Similarity: 111/241 - (46%)
• Gaps: 53/241 - (21%)

  Fly     2 DKG-------------TMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEAR 53
            |||             :.|::|||.||.|.:.||||||..|||..|||:..|||:||..:|||||
Mouse    71 DKGQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135

  Fly    54 VQVWFQNRRAKWRKQEK--------------IGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGG 104
            |:|||:||||||||:|:              ..||...|.:  :....||::.|..|...::|..
Mouse   136 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDD--MYPGYSYNNWAAKGLTSASLST 198

  Fly   105 GGTLLP-----DTPPQSSNSL---DNELKASYGTGAMSPSRLS--PNIFLNL--NIDHLGLERGG 157
            ..  .|     :..|.||.|:   .|.:.:...:.:|.||.::  |...||.  |:::|......
Mouse   199 KS--FPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN 261

  Fly   158 SGLSMEWSTYPPQTQAQTHPQMDSDN--------QLQQHPPQQHAS 195
            |.:......|.|.|....:  .|:.|        :.:||....:||
Mouse   262 SAVPTPACPYAPPTPPYVY--RDTCNSSLASLRLKAKQHSSFGYAS 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	37/55 (67%)
Pitx2	NP_001035967.1	Homeodomain	93..149	CDD:459649	37/55 (67%)
		OAR	282..299	CDD:461067	3/16 (19%)