Protein Alignment Pph13 and Hoxd3

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 243
• Identity: 64/243 - (26%)
• Similarity: 93/243 - (38%)
• Gaps: 43/243 - (17%)

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66
            ||.......:|.||.:.:.||.|||:.|....|.....|.|:|..::|||.::::||||||.|::
Mouse   187 DKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 251

  Fly    67 KQEKIGGL----GGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPD--TPPQSSNSLDNELK 125
            |.:|..|:    .|...|.:..|..:....|..|||....|    |..|  :||..:.|..|
Mouse   252 KDQKAKGILHSPAGQSPERSPPLGGAAGHVAYSGQLPPVPG----LAYDAPSPPAFAKSQPN--- 309

  Fly   126 ASYGTGA-------------------MSPSRLSPN--IFLNLNIDHLGLERGGSGLSMEWSTYPP 169
             .||..|                   ..|..::.|  .|.:.|:....:..||:.:.....|..|
Mouse   310 -MYGLAAYTAPLSSCLPQQKRYPAPEFEPHPMASNGGGFASANLQGSPVYVGGNFVDSMAPTSGP 373

  Fly   170 --QTQAQTHPQMDS-DNQLQQHPPQQH-----ASDPIHAGSSSHHQQQ 209
              .....:||...| |.......|..|     ...|.:...|:||..|
Mouse   374 VFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	23/55 (42%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		2/10 (20%)
		Antp-type hexapeptide	161..166
		Homeodomain	196..252	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		4/21 (19%)
		DUF4074	370..431	CDD:463833	13/52 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433		5/21 (24%)