Protein Alignment Pph13 and Dmbx1

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: XP_017175446.1
• Gene: Dmbx1 / 140477
• MGIID: 2153518
• Length: 389
• Species: Mus musculus
• Alignment Length: 355
• Identity: 98/355 - (27%)
• Similarity: 138/355 - (38%)
• Gaps: 65/355 - (18%)

  Fly     4 GTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQ 68
            |:..|||||.||.|...||:.||:.||:||||||..||.||:..:|.||||||||:|||||:||:
Mouse    73 GSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKK 137

  Fly    69 ---------EKIGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNEL 124
                     :|.....|.:.||.::...|  |:.:..:....|..|     |.|.:...||..:
Mouse   138 QRSLQKEQLQKQKEAEGSHGEGKVEAPAS--DTQLETEQPPGLPSG-----DPPAELQLSLSEQ- 194

  Fly   125 KASYGTGAMSPSRLSPNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHP 189
                     |.|..:|...|:...|....|..........|..|...:..  |:.||...|...|
Mouse   195 ---------SASESAPEDQLDREEDSRAEEPKAEKSPGSESKVPGCKRGS--PKADSPGSLAITP 248

  Fly   190 --PQQHASDPIHAGSSS-----HHQQQQQQHQQEQHNPQLHPGLEFAASLSLDMTDGSSAYDEMK 247
              |......|.|:.|||     ..|:|.:||....:|...:...|............::|   :.
Mouse   249 AAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAA---VP 310

  Fly   248 FLSVDVDQFTIDSFKADCILSMEQSQMQAYGGHSQLVGSSNELCLDGIGMSSFGMEEGEPKSPPS 312
            :|.|::...:    ...| .|..||...|...|..:.||..                 .|..|..
Mouse   311 YLGVNMAPLS----SLHC-QSYYQSLSAAAAAHQGVWGSPL-----------------LPAPPTG 353

  Fly   313 LLVLDKSLPSLSIGVEGIADLVEQLHHHQH 342
            |.....:|.|.:..:|.:     :|...||
Mouse   354 LAPASAALNSKTTSIENL-----RLRAKQH 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	35/55 (64%)
Dmbx1	XP_017175446.1	Homeodomain	80..136	CDD:459649	35/55 (64%)