Protein Alignment Pph13 and Dlx3

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_034185.1
• Gene: Dlx3 / 13393
• MGIID: 94903
• Length: 287
• Species: Mus musculus
• Alignment Length: 192
• Identity: 57/192 - (29%)
• Similarity: 93/192 - (48%)
• Gaps: 46/192 - (23%)

  Fly     8 RKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIG 72
            :|.|:.||.:::.||..|:|.||:..|..:..|.|||.::.||:.:|::||||||:|::|.
Mouse   127 KKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKL---- 187

  Fly    73 GLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAMSPSR 137
                 ||.|.:.|:.|.::|      ||       :..::||  |.:|.:  .:|:.|.|.:.:.
Mouse   188 -----YKNGEVPLEHSPNNS------DS-------MACNSPP--SPALWD--TSSHSTPAPARNP 230

  Fly   138 LSPNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQ----QHAS 195
            |.|.:..:.:.::|                ...|.:..|.|..|...|||.|||    .|||
Mouse   231 LPPPLPYSASPNYL----------------DDPTNSWYHTQNLSGPHLQQQPPQPATLHHAS 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	24/55 (44%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:463567
		COG5576	<109..224	CDD:227863	39/122 (32%)
		Homeodomain	130..186	CDD:459649	24/55 (44%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:O60479	131..181		20/49 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		28/115 (24%)