Protein Alignment Pph13 and Vsx1

DIOPT Version :10

• Sequence 1: NP_477330.1
• Gene: Pph13 / 33239
• FlyBaseID: FBgn0023489
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_473409.1
• Gene: Vsx1 / 114889
• MGIID: 1890816
• Length: 363
• Species: Mus musculus
• Alignment Length: 228
• Identity: 80/228 - (35%)
• Similarity: 97/228 - (42%)
• Gaps: 71/228 - (31%)

  Fly     7 KRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKI 71
            |||:||:||.|...||:|||:||...|||||:.||.||.:.:|.|.|:|||||||||||||:||.
Mouse   168 KRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYAREMLAAKTELPEDRIQVWFQNRRAKWRKREKR 232

  Fly    72 GGLGGDYKEGALDLDVSYDDSAVLGQ--LDSALGGGGTLLPDTPPQSSNSLDNEL--------KA 126
            .|                 .|:|:.:  |..|:......|||:...|::||....        |.
Mouse   233 WG-----------------GSSVMAEYGLYGAMVRHCIPLPDSVLNSADSLQGSCAPWLLGMHKK 280

  Fly   127 SYGTGAMSPSRLSPNIFLNL-NIDHL---------GLERG-------------------GSGLSM 162
            |  ||...|.  |.:....| ..|||         |.|||                   .|....
Mouse   281 S--TGMRKPE--SEDKLAGLWEFDHLKKGANKDEDGPERGPDETTQNPENSLEDVAIDLSSSSRQ 341

  Fly   163 EWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHAS 195
            |....||          .|..||.| |||..||
Mouse   342 ETKKMPP----------GSSTQLPQ-PPQVGAS 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeodomain	11..67	CDD:459649	35/55 (64%)
Vsx1	NP_473409.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Octapeptide motif	31..38
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..166
		Nuclear localization signal. /evidence=ECO:0000255	168..173		3/4 (75%)
		Homeodomain	172..228	CDD:459649	35/55 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..363		18/73 (25%)