DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pph13 and alx1

DIOPT Version :9

Sequence 1:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_002931669.1	Gene:	alx1 / 100489661	XenbaseID:	XB-GENE-853095	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	209	Identity:	75/209 - (35%)
Similarity:	100/209 - (47%)	Gaps:	43/209 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66
            |......|:||:||||.:|||:|||:.||:||||||:.||:||:|.:||||||||||||||||||
Frog   124 DSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWR 188

  Fly    67 KQEKIGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLP--DTPPQSSNSL--DNELKAS 127
            |:|:.|.:.......|...|:|                   :||  |:.||..|:|  .|....|
Frog   189 KRERYGQIQQAKSHFAATYDIS-------------------VLPRADSYPQIQNNLWAGNPSGGS 234

  Fly   128 YGTGAMSPSRLSPNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQ 192
            ..|..|.|...|..:               :..|....|..|.|....|     .||....|...
Frog   235 VVTSCMLPREPSACM---------------TPYSHSTRTDSPYTSFTNH-----QNQFSHVPLNN 279

  Fly   193 HASDPIHAGSSSHH 206
            ..::.:.:||::.|
Frog   280 FFTESLLSGSANGH 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	39/51 (76%)
alx1	XP_002931669.1	Homeobox	135..189	CDD:365835	40/53 (75%)
alx1	XP_002931669.1	OAR	302..320	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5874
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040