DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pph13 and mxtx1

DIOPT Version :9

Sequence 1:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_571635.2	Gene:	mxtx1 / 100149566	ZFINID:	ZDB-GENE-000710-7	Length:	309	Species:	Danio rerio

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	90/223 - (40%)	Gaps:	42/223 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GTMKRK-QRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRK 67
            |.:.|. .||.||:|:...::.|...|:...||.:..||.|:....|.|:|:|||||||||:..|
Zfish    17 GAVSRSASRRKRTSFSKEHVELLRATFETDPYPGISLRESLSQTTGLPESRIQVWFQNRRARTLK 81

  Fly    68 QEKIGGLGGDYKEGALDL----DVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASY 128
            .:     ||.......||    ::......:..:.:.:.|..|||. ..||...:.:..|::...
Zfish    82 CK-----GGKKPLWQTDLPAYNNMQTSPMQIHRKNNESSGATGTLC-SPPPAYPDRIKEEMEKDA 140

  Fly   129 GTGAMSPSRLS---------PNIFLN------------LNIDH-----LGLERG-GSGLSMEWST 166
            ..|..:||.:|         |:...:            |:.:|     .|:..| .|.:|..||.
Zfish   141 VCGCDTPSSMSISDDSGYCTPSYHQSRAIQSHMSPSPLLSPEHQMPPNWGVRYGRRSPMSSMWSP 205

  Fly   167 YPPQTQAQT----HPQMDSDNQLQQHPP 190
            |..:..|..    :...:..|.||...|
Zfish   206 YHLEAYACNPGFFYSHSEKHNTLQPLTP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	22/51 (43%)
mxtx1	NP_571635.2	HOX	24..78	CDD:197696	23/53 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.870