DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pph13 and rax

DIOPT Version :9

Sequence 1:	NP_477330.1	Gene:	Pph13 / 33239	FlyBaseID:	FBgn0023489	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	XP_002936715.1	Gene:	rax / 100038124	XenbaseID:	XB-GENE-492665	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	231	Identity:	80/231 - (34%)
Similarity:	115/231 - (49%)	Gaps:	43/231 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWR 66
            |:...|:|.||.||||.|.||.||||||:::|||||:.|||||::::|.|.||||||||||||||
Frog   123 DEQQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQVWFQNRRAKWR 187

  Fly    67 KQEKIGGLGGDYKEGALDLDVS---YDDSAVL----GQLDSALGGGGTLLP-DT--PPQSSNSLD 121
            :|||              |:|:   ..||.:|    ....||:....:.|| |:  .|..|||..
Frog   188 RQEK--------------LEVTSMKLQDSPILSFNRSPQPSAMSAISSSLPLDSWLTPSISNSTA 238

  Fly   122 NELKASYGTGAMS-PSRLSPNIFLN-LNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQ 184
            .:....:.|...| |...:|..|:| .::.|.....|..|        ||.      |.....:.
Frog   239 LQSLPGFVTSPPSLPGSYTPPPFINPASVGHALQPLGAMG--------PPP------PYQCGASF 289

  Fly   185 LQQHPPQQHASDPIHAGSSSHHQQQQQQHQQEQHNP 220
            :.::|.::  :|| ...|.:..:.:.::|.|....|
Frog   290 VDKYPLEE--ADP-RNNSIASLRMKAKEHIQSIGKP 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pph13	NP_477330.1	Homeobox	14..66	CDD:278475	37/51 (73%)
rax	XP_002936715.1	Homeobox	135..188	CDD:365835	38/52 (73%)
rax	XP_002936715.1	OAR	299..315	CDD:367680	3/16 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D454642at33208
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920