Protein Alignment Ipk2 and IPMK

DIOPT Version :9

• Sequence 1: NP_608535.1
• Gene: Ipk2 / 33236
• FlyBaseID: FBgn0031267
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: XP_011537867.1
• Gene: IPMK / 253430
• HGNCID: 20739
• Length: 419
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 113/419 - (26%)
• Similarity: 174/419 - (41%)
• Gaps: 144/419 - (34%)

  Fly     6 QELPEGFRQ--------------LKTQVAGHTFEESNAEAVGLLQDSKAGCVLKPLGKPECGERE 56
            :..|||..|              |..|||||.:   ..:.||:||... |.|||.|..|..|.||
Human    26 ESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMY---GKDKVGILQHPD-GTVLKQLQPPPRGPRE 86

  Fly    57 LRFYESLAEAGASGDND-LLALLRGHVPRFYG-------PLKLVVNRRERTFLRLEDLTRSYAKP 113
            |.||..::|..|:...| :|..||.::|::||       |..|        :|:|||:|..:.||
Human    87 LEFYNMVSEVYAADCFDGVLLELRKYLPKYYGIWSPPTAPNDL--------YLKLEDVTHKFNKP 143

  Fly   114 CVMDVKMGKRTWDPESSPNKRKVEEAKYVMCKQKLGLCLPGFQVYLPKEEHTQETTILRHGKDYG 178
            |:||||:|::::||.:|..|.:.:.:||.: .:::|..:.|.:||     |....:.....:.||
Human   144 CIMDVKIGQKSYDPFASSEKIQQQVSKYPL-MEEIGFLVLGMRVY-----HVHSDSYETENQHYG 202

  Fly   179 KSLNVEGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQLQEILAWFQRQRLLHFYASSLLICY 243
            :||..|..|..::.||:......|...|..       ::::::||.||:.|:.|:|||||||..|
Human   203 RSLTKETIKDGVSRFFHNGYCLRKDAVAAS-------IQKIEKILQWFENQKQLNFYASSLLFVY 260

  Fly   244 DYS---------------------RLADPP-KPLINGYH-------------------------- 260
            :.|                     :|:|.. ....|.:|
Human   261 EGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHR 325

  Fly   261 ---------------QNDDDPATW--------------------------------VRVKMIDFA 278
                           :|.:....|                                |.|:|||||
Human   326 KIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPTGCQEIAEVEVRMIDFA 390

  Fly   279 HVYPAEQGLPDENYMFGLQSLIEVVQSIL 307
            ||:|:  ...||.|::||:.||.|::|||
Human   391 HVFPS--NTIDEGYVYGLKHLISVLRSIL 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ipk2	NP_608535.1	IPK	100..304	CDD:281727	73/298 (24%)
IPMK	XP_011537867.1	IPK	130..414	CDD:281727	73/298 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151832
Domainoid	1	1.000	127	1.000	Domainoid score	I5382
eggNOG	1	0.900	-	-		E1_KOG1620
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H76214
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4269
Isobase	1	0.950	-	0	Normalized mean entropy	S4071
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452635at33208
OrthoFinder	1	1.000	-	-		FOG0003587
OrthoInspector	1	1.000	-	-		oto90959
orthoMCL	1	0.900	-	-		OOG6_104761
Panther	1	1.100	-	-	LDO	PTHR12400
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3597
SonicParanoid	1	1.000	-	-		X2060
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.740