DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ipk2 and Y22D7AR.6

DIOPT Version :9

Sequence 1:	NP_608535.1	Gene:	Ipk2 / 33236	FlyBaseID:	FBgn0031267	Length:	309	Species:	Drosophila melanogaster
Sequence 2:	NP_001380063.1	Gene:	Y22D7AR.6 / 175320	WormBaseID:	WBGene00021260	Length:	323	Species:	Caenorhabditis elegans

Alignment Length:	347	Identity:	81/347 - (23%)
Similarity:	138/347 - (39%)	Gaps:	114/347 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QVAGHTFEESNAEAVGLLQDSKAGCVLKPLGKPECGERELRFYESLAE---------------AG 67
            ||.|||...|...          |.:|||     |.|||:.||:.:.:               :.
Worm    28 QVGGHTPFTSLPN----------GHLLKP-----CEEREILFYQKMPKILKSIAPLCCSTIQGSS 77

  Fly    68 ASGDNDLLALLRGH------VPRFY--GPLKLVVNRRE--RTFLRLEDLTRSYAKPCVMDVKMGK 122
            .|..:|..:..|.|      :|...  .|   ::|:|:  :.|:.|.|||.....|.::|:|:|.
Worm    78 VSTLDDSCSNCRHHQLENVVIPESIEGSP---ILNKRKLSKNFIVLSDLTYRMKSPRILDLKLGT 139

  Fly   123 RTWDPESSPNKRKVEEAKYVMCK----QKLGLCLPGFQV----------------------YLPK 161
            |....:::.:|.....||   |:    ..||:.|.|.::                      :.||
Worm   140 RQHGDQATVSKIACMTAK---CQATTSATLGIRLCGMKIPFLEQNSQNFAPNFAPNSAAPNFAPK 201

  Fly   162 EEHTQETTILRHGKDYGKSLNVEGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQL---QEIL 223
            .|       :...|..|:|::.......:..||:..           |.:|:||.|:|   :::|
Worm   202 SE-------ISINKYMGRSMDKTDLFLAVKQFFDVP-----------EAVLEEVERRLLGIRDVL 248

  Fly   224 AWFQRQRLLHFYASSLLICYDYSRLADPPKPLINGYHQNDDDPATWVRVKMIDFAH-VYPAEQGL 287
            ......||   :.:||||..: |..:|...|:.|           .||:|::|||: .:...||.
Worm   249 CGADGVRL---FGASLLIVIE-SNFSDSQLPIDN-----------LVRIKVVDFANATFGGLQGD 298

  Fly   288 P-----DENYMFGLQSLIEVVQ 304
            .     |:..:.||::|:|:|:
Worm   299 SFYDGRDDGSILGLETLLEIVK 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ipk2	NP_608535.1	IPK	100..304	CDD:281727	56/238 (24%)
Y22D7AR.6	NP_001380063.1	IPK	117..320	CDD:397715	56/238 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1620
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D452635at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3597
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850