Protein Alignment Ipk2 and IP6K3

DIOPT Version :10

• Sequence 1: NP_608535.1
• Gene: Ipk2 / 33236
• FlyBaseID: FBgn0031267
• Length: 309
• Species: Drosophila melanogaster
• Sequence 2: NP_473452.2
• Gene: IP6K3 / 117283
• HGNCID: 17269
• Length: 410
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 80/234 - (34%)
• Similarity: 115/234 - (49%)
• Gaps: 41/234 - (17%)

  Fly    94 NRRERTFLRLEDLTRSYAKPCVMDVKMGKRTWDPESSPNKRKVEEAKYVMCKQKLGLCLP----G 154
            |:|.| ||.||::...|..|||:|:|||.|....::|..|:.....|   |.|....||.    |
Human   193 NKRHR-FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRK---CAQSTSACLGVRICG 253

  Fly   155 FQVYLPKEEHTQETTILRHGKDYGKSLNVEGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQL 219
            .|||     .|.:...|...|.||:.|:||||:|.:..|.:   :.|..||.    ||:.:|.||
Human   254 MQVY-----QTDKKYFLCKDKYYGRKLSVEGFRQALYQFLH---NGSHLRRE----LLEPILHQL 306

  Fly   220 QEILAWFQRQRLLHFYASSLLICYDYSRLADPPKPLINGYHQNDDDPA---------TWVRVKMI 275
            :.:|:..:.|....||:||||:.||..   :||:......|.::...|         |.|.::||
Human   307 RALLSVIRSQSSYRFYSSSLLVIYDGQ---EPPERAPGSPHPHEAPQAAHGSSPGGLTKVDIRMI 368

  Fly   276 DFAHV--------YPAEQGLPDENYMFGLQSLIEVVQSI 306
            ||||.        :....| ||..|:|||::||.::|.|
Human   369 DFAHTTYKGYWNEHTTYDG-PDPGYIFGLENLIRILQDI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ipk2	NP_608535.1	IPK	100..304	CDD:397715	75/224 (33%)
IP6K3	NP_473452.2	IPK	198..404	CDD:397715	75/224 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..358		4/27 (15%)