DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ipk2 and IP6K3

DIOPT Version :9

Sequence 1:NP_608535.1 Gene:Ipk2 / 33236 FlyBaseID:FBgn0031267 Length:309 Species:Drosophila melanogaster
Sequence 2:NP_001136355.1 Gene:IP6K3 / 117283 HGNCID:17269 Length:410 Species:Homo sapiens


Alignment Length:234 Identity:80/234 - (34%)
Similarity:115/234 - (49%) Gaps:41/234 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    94 NRRERTFLRLEDLTRSYAKPCVMDVKMGKRTWDPESSPNKRKVEEAKYVMCKQKLGLCLP----G 154
            |:|.| ||.||::...|..|||:|:|||.|....::|..|:.....|   |.|....||.    |
Human   193 NKRHR-FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRK---CAQSTSACLGVRICG 253

  Fly   155 FQVYLPKEEHTQETTILRHGKDYGKSLNVEGFKQTMALFFNASTSDSKSRRAGCELLLKEVLRQL 219
            .|||     .|.:...|...|.||:.|:||||:|.:..|.:   :.|..||.    ||:.:|.||
Human   254 MQVY-----QTDKKYFLCKDKYYGRKLSVEGFRQALYQFLH---NGSHLRRE----LLEPILHQL 306

  Fly   220 QEILAWFQRQRLLHFYASSLLICYDYSRLADPPKPLINGYHQNDDDPA---------TWVRVKMI 275
            :.:|:..:.|....||:||||:.||..   :||:......|.::...|         |.|.::||
Human   307 RALLSVIRSQSSYRFYSSSLLVIYDGQ---EPPERAPGSPHPHEAPQAAHGSSPGGLTKVDIRMI 368

  Fly   276 DFAHV--------YPAEQGLPDENYMFGLQSLIEVVQSI 306
            ||||.        :....| ||..|:|||::||.::|.|
Human   369 DFAHTTYKGYWNEHTTYDG-PDPGYIFGLENLIRILQDI 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ipk2NP_608535.1 IPK 100..304 CDD:281727 75/224 (33%)
IP6K3NP_001136355.1 IPK 198..404 CDD:309046 75/224 (33%)
Substrate binding. /evidence=ECO:0000250 211..219 5/7 (71%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 333..358 4/27 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1620
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D452635at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3597
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.850

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