| Sequence 1: | NP_477294.2 | Gene: | Nle / 33234 | FlyBaseID: | FBgn0021874 | Length: | 488 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060058.1 | Gene: | WDR5 / 11091 | HGNCID: | 12757 | Length: | 334 | Species: | Homo sapiens |
| Alignment Length: | 388 | Identity: | 106/388 - (27%) |
|---|---|---|---|
| Similarity: | 165/388 - (42%) | Gaps: | 94/388 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 105 VRPVTRCTSSMPGHAEAVVSLNFSPDGAHLASGSGDTTVRLWDLNTETPHFTCTGHKQWVLCVSW 169
Fly 170 APDGKRLASGCKAGSIIIWDPETGQQKGRPLSGHKKHINCLAWEPYHRDPECRKLASASGDGDCR 234
Fly 235 IWDVKLGQCLMNIAGHTNAVTAVRWGGAG-LIYTSSKDRTVKMWRAADGILCRTFSGHAHWVNNI 298
Fly 299 ALSTDYVLRTGPFHPVKDRSKSHLSLSTEELQESALKRYQAVCPDEVESLVSCSDDNTLYLWRNN 363
Fly 364 QNKCVERMTGHQNVVNDVKYSPDVKLIASASFDKSVRLWRASDGQYMATFRGHVQAVYTVAWS-- 426
Fly 427 -ADSRLIVSGSKDSTLKVWSVQTKKLAQELPGHADEVFGVDWAPDGSRVASGG--KDKVIKLW 486 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Nle | NP_477294.2 | NLE | 22..82 | CDD:462380 | |
| WD40 | 84..486 | CDD:441893 | 104/386 (27%) | ||
| WD40 repeat | 123..159 | CDD:293791 | 12/35 (34%) | ||
| WD40 repeat | 164..202 | CDD:293791 | 10/37 (27%) | ||
| WD40 repeat | 208..249 | CDD:293791 | 14/40 (35%) | ||
| WD40 repeat | 254..289 | CDD:293791 | 13/35 (37%) | ||
| WD40 repeat | 296..372 | CDD:293791 | 3/75 (4%) | ||
| WD40 repeat | 378..414 | CDD:293791 | 14/35 (40%) | ||
| WD40 repeat | 420..456 | CDD:293791 | 12/38 (32%) | ||
| WD40 repeat | 462..486 | CDD:293791 | 8/25 (32%) | ||
| WDR5 | NP_060058.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..31 | 106/388 (27%) | |
| WD40 | <36..330 | CDD:441893 | 102/381 (27%) | ||
| WD 1 | 43..82 | 15/38 (39%) | |||
| WD40 repeat | 48..85 | CDD:293791 | 13/36 (36%) | ||
| WD 2 | 85..126 | 12/41 (29%) | |||
| WD40 repeat | 91..127 | CDD:293791 | 10/36 (28%) | ||
| WD 3 | 128..168 | 15/44 (34%) | |||
| WD40 repeat | 132..168 | CDD:293791 | 14/40 (35%) | ||
| WD 4 | 169..208 | 13/38 (34%) | |||
| WD40 repeat | 175..210 | CDD:293791 | 12/96 (13%) | ||
| WD 5 | 212..253 | 17/60 (28%) | |||
| WD40 repeat | 217..253 | CDD:293791 | 14/35 (40%) | ||
| WD 6 | 256..296 | 11/39 (28%) | |||
| WD40 repeat | 261..298 | CDD:293791 | 11/36 (31%) | ||
| WD 7 | 299..333 | 13/32 (41%) | |||
| WD40 repeat | 304..330 | CDD:293791 | 8/25 (32%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||