DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11835 and BTF3

DIOPT Version :9

Sequence 1:	NP_001259835.1	Gene:	CG11835 / 33232	FlyBaseID:	FBgn0031264	Length:	795	Species:	Drosophila melanogaster
Sequence 2:	NP_001032726.1	Gene:	BTF3 / 689	HGNCID:	1125	Length:	206	Species:	Homo sapiens

Alignment Length:	161	Identity:	97/161 - (60%)
Similarity:	117/161 - (72%)	Gaps:	9/161 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNVEKLKRLQAQVRIGGKGTPRRKKKVMHQTAATDDKKLQSSLKKLSVSTIPGIEEVNIIKDDLT 65
            ||.|||.:||||||||||||.||||||:|:||..||||||.|||||.|:.|.||||||:..:..|
Human    50 MNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGT 114

  Fly    66 VIHFNNPKAQASLSANTFAVTGHGETRKVVEMLPDILPQLGQETVVQLRMYANAMNSQKGAPGSG 130
            ||||||||.||||:||||.:|||.||:::.||||.||.|||.:::..||..|.|:..|     |.
Human   115 VIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQ-----SV 174

  Fly   131 DGPLP----AEEDDDVPLLVGDFDEVAKVEA 157
            ||..|    .::||:||.||.:|||.:|.||
Human   175 DGKAPLATGEDDDDEVPDLVENFDEASKNEA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11835	NP_001259835.1	NAC	38..91	CDD:280093	36/52 (69%)
BTF3	NP_001032726.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		NAC	87..140	CDD:376630	36/52 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..206		17/41 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2240
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37453
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1435264at2759
OrthoFinder	1	1.000	-	-		FOG0000935
OrthoInspector	1	1.000	-	-		mtm8606
orthoMCL	1	0.900	-	-		OOG6_101091
Panther	1	1.100	-	-	O	PTHR10351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R790
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.810