DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11835 and Cx3cl1

DIOPT Version :9

Sequence 1:	NP_001259835.1	Gene:	CG11835 / 33232	FlyBaseID:	FBgn0031264	Length:	795	Species:	Drosophila melanogaster
Sequence 2:	NP_033168.2	Gene:	Cx3cl1 / 20312	MGIID:	1097153	Length:	395	Species:	Mus musculus

Alignment Length:	397	Identity:	80/397 - (20%)
Similarity:	130/397 - (32%)	Gaps:	124/397 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 AKVPETTNPSE---NPKEKQENKKGQAKNNKKGDPQTNKDKTNKSKDQAKGQPAPQANKETTQAA 250
            |.|.|||....   :||||......:..:::......|..|..|..|..    .|.....|...:
Mouse    62 AIVLETTQHRRFCADPKEKWVQDAMKHLDHQAAALTKNGGKFEKRVDNV----TPGITLATRGLS 122

  Fly   251 QALKQNPSKPAVQQKKDQVLAVDQKIEANGAIQKAQQPKPAETKSTDQKVEPKSAEKQVDKAKPI 315
            .:....|....::....::..:.|  ||.|.:..:|:|..|.|.|:
Mouse   123 PSALTKPESATLEDLALELTTISQ--EARGTMGTSQEPPAAVTGSS------------------- 166

  Fly   316 EQTKTKESKVEHPKPAQKQLDQNTQAKPTAERS-EAKPVVPTPEPQKSAPPAVQTLAQIVALPAE 379
              ..|.|::           |....|||.:..| ||..:..|..|.    |||.
Mouse   167 --LSTSEAQ-----------DAGLTAKPQSIGSFEAADISTTVWPS----PAVY----------- 203

  Fly   380 KPANEAVAAPKAEEQKKDSSGPAKVEPAITPSAPQPVTTAEPPKSALKQDSPPKSAPKQGSPPKN 444
                ::.::..|||:..:|       |:.|..:||..||           ||       .:|.:|
Mouse   204 ----QSGSSSWAEEKATES-------PSTTAPSPQVSTT-----------SP-------STPEEN 239

  Fly   445 VPKQESPPQSAPKQDSPPKGAPKQDSPPKGAPKQDSPPKGAPKQDSAPQQKTPPPVKQEVAPAKQ 509
            |..:..||....:..||.|....::..|.....         .|:..|.....|    .|||...
Mouse   240 VGSEGQPPWVQGQDLSPEKSLGSEEINPVHTDN---------FQERGPGNTVHP----SVAPISS 291

  Fly   510 DEPPAKQDAPPAKQDAPVPVPEVIK--TLAPEVPNVSQAPAQPQGQAALASEKPADAPKAIEEPK 572
            :|.|:               ||::.  :.||::.....|.|.||..:.|.:..|        :.:
Mouse   292 EETPS---------------PELVASGSQAPKIEEPIHATADPQKLSVLITPVP--------DTQ 333

  Fly   573 AAPKKES 579
            ||.::::
Mouse   334 AATRRQA 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11835	NP_001259835.1	NAC	38..91	CDD:280093
Cx3cl1	NP_033168.2	Chemokine_CX3C	25..100	CDD:238172	9/37 (24%)
		Chemokine and involved in interaction with ITGAV:ITGB3 and ITGA4:ITGB1. /evidence=ECO:0000250\|UniProtKB:P78423	25..100		9/37 (24%)
		Mucin-like stalk	101..336		69/352 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	148..180		10/63 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..305		33/171 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000