DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tspo and TSPO2

DIOPT Version :9

Sequence 1:	NP_608531.1	Gene:	Tspo / 33231	FlyBaseID:	FBgn0031263	Length:	185	Species:	Drosophila melanogaster
Sequence 2:	NP_001010873.1	Gene:	TSPO2 / 222642	HGNCID:	21256	Length:	170	Species:	Homo sapiens

Alignment Length:	168	Identity:	58/168 - (34%)
Similarity:	91/168 - (54%)	Gaps:	4/168 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LRIAGA--VILPNLGGIYNGRLTRQHLQSWYANLKFPSFKPPNSVFAPMWISLYAGMGYGSYLVW 73
            :|:.||  |:||:||.|.....||.|:..|....:..|:.|...|...:..::|:.:||.|||||
Human     1 MRLQGAIFVLLPHLGPILVWLFTRDHMSGWCEGPRMLSWCPFYKVLLLVQTAIYSVVGYASYLVW 65

  Fly    74 RDGGGFAGEAAKLPLIAYGTQLALNWAWTPIFFGQHNIKGGLIDIVALTAAASACGVLFYRVNKT 138
            :|.||..|....|||..|..||.::|....:||..||....|:.::.|.....:..::::.:||.
Human    66 KDLGGGLGWPLALPLGLYAVQLTISWTVLVLFFTVHNPGLALLHLLLLYGLVVSTALIWHPINKL 130

  Fly   139 AGLLFVPYVAWLGFATALNYAIWK--LNPEKEQAPKDE 174
            |.||.:||:|||...:||.|.:|:  |.|..:..|.::
Human   131 AALLLLPYLAWLTVTSALTYHLWRDSLCPVHQPQPTEK 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tspo	NP_608531.1	TspO_MBR	17..161	CDD:281118	51/143 (36%)
TSPO2	NP_001010873.1	TspO_MBR	10..154	CDD:376985	50/143 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52353
OrthoDB	1	1.010	-	-		D1592225at2759
OrthoFinder	1	1.000	-	-		FOG0003750
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10057
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.820