DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets21C and erfl1

DIOPT Version :9

Sequence 1:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	XP_009290629.1	Gene:	erfl1 / 558126	ZFINID:	ZDB-GENE-090529-3	Length:	473	Species:	Danio rerio

Alignment Length:	267	Identity:	93/267 - (34%)
Similarity:	115/267 - (43%)	Gaps:	69/267 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 QIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYD 318
            |||||.|:||||........|:|:|..|||.:.|||||||.||.||.||:||||||||||||||:
Zfish    40 QIQLWHFILELLQKEEYQGVIAWQGDYGEFVIKDPDEVARLWGIRKCKPHMNYDKLSRALRYYYN 104

  Fly   319 KNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASS-MLGSYNHHAGGAM-------------- 368
            |.|:.|..|||:.|||:|..::.......   |.||| .|.:.||..|||.
Zfish   105 KRILHKTKGKRFTYKFNFSKVVLVNYPLL---DMASSPFLLAQNHFNGGAATPDCSPVTPEALQT 166

  Fly   369 ------QLGRHPPPLHHH-----------------------PQHSHPHHQLG----QPHFLHPHH 400
                  :.||.|.....:                       |.:|.|...||    .|.|.:|..
Zfish   167 LFPRLPESGRGPSLFERNAGAPGPDGDKLRLDTFPFLGSGAPCYSKPPSLLGPYPRSPSFDYPWG 231

  Fly   401 SSP-------ASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAPFQ-----GGTAGVDPAR 453
            .:|       .:|...|  |..|..||...|.|.    .:|.|....||.     |..||.:...
Zfish   232 FNPYLPGAFSLNNCPKL--PPGSLYSSHFYPNQL----QSSLSQLPHPFSSLLPPGDAAGTERGG 290

  Fly   454 TSTSSAG 460
            |:.|:.|
Zfish   291 TNGSAGG 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	53/84 (63%)
erfl1	XP_009290629.1	ETS	40..122	CDD:197710	52/81 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910