DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets21C and Elk3

DIOPT Version :9

Sequence 1:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001102213.1	Gene:	Elk3 / 362871	RGDID:	1307764	Length:	408	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	86/292 - (29%)
Similarity:	116/292 - (39%)	Gaps:	84/292 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 IQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDK 319
            |.||||||.||.|..:.:.|.|....|||:|:..:|||:.||.||.|.|||||||||||||||||
  Rat     5 ITLWQFLLHLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALRYYYDK 69

  Fly   320 NIMTKVHGKRYAYKF---------DFHGLMAA----------CQAQAQGGDPASSMLGS------ 359
            ||:.||.|:::.|||         |.|.:..:          |:...:|.:.....|.|
  Rat    70 NIIKKVIGQKFVYKFVSFPDILKMDPHAVEISRESLLLQDSDCKVSPEGREIHKHGLSSLKSASR 134

  Fly   360 --YNH----------------HAGGAMQLGRHPPPLHHHPQHSHPHHQL----------GQPHFL 396
              |.|                .|..|::..:...|....|    |..::          ...|..
  Rat   135 NEYIHSGLYSSFTINSLQNAPEAFKAIKTEKLEEPCDDSP----PVEEVRTVIRFVTNKTDKHIT 195

  Fly   397 HPHHSSPASNS-----------------SSLGFP-----SSSTASSQASPGQAPAS--SSASTSN 437
            .|..|.|:::.                 |||..|     ||::.||..||..:|.|  .|...|.
  Rat   196 RPVVSLPSTSEAAAAASAFLASSVSAKISSLMLPNAASVSSASPSSSRSPSLSPNSPLPSEHRSL 260

  Fly   438 FTAPFQGGTAGVDPARTSTSSAGNYDQGPVTP 469
            |   .:......|.......|:|:..:.|..|
  Rat   261 F---LEAACHDADSLEPLNLSSGSKTKSPSLP 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	51/92 (55%)
Elk3	NP_001102213.1	ETS	5..89	CDD:197710	49/83 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810