DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets21C and Etv3

DIOPT Version :9

Sequence 1:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001076787.1	Gene:	Etv3 / 27049	MGIID:	1350926	Length:	513	Species:	Mus musculus

Alignment Length:	238	Identity:	86/238 - (36%)
Similarity:	113/238 - (47%)	Gaps:	61/238 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 AQGSGG--QIQLWQFLLELLADSSNANAISW-EGQSGEFRLIDPDEVARRWGERKAKPNMNYDKL 309
            |:.|.|  |||||.|:||||......:.|:| :|:.|||.:.|||||||.||.||.||.||||||
Mouse    26 AESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKL 90

  Fly   310 SRALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSY---NHHAGGAMQLG 371
            ||||||||:|.|:.|..|||:.|||:|:.|                ::.:|   |..:.|.:...
Mouse    91 SRALRYYYNKRILHKTKGKRFTYKFNFNKL----------------VMPNYPFINIRSSGVVPQS 139

  Fly   372 RHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFP--SSSTASSQASPGQAPASS-SA 433
            ..|.|                            :.||...||  .|.:.:....||:..||| ||
Mouse   140 APPVP----------------------------TASSRFHFPPLDSHSPTGDVQPGRFSASSLSA 176

  Fly   434 STSNFTAPFQGGTAG--VDPARTSTSSAGNYDQG-PVTPTTNA 473
            |     .|..|.|..  |:|:.....||.::.:| ...|:.||
Mouse   177 S-----GPESGVTTDRKVEPSDLEDGSASDWHRGMDFMPSRNA 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	53/85 (62%)
Etv3	NP_001076787.1	ETS	34..120	CDD:197710	53/85 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	138..202		22/96 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..513
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810