Protein Alignment Ets21C and GABPA

DIOPT Version :10

• Sequence 1: NP_523445.1
• Gene: Ets21C / 33229
• FlyBaseID: FBgn0005660
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_002031.2
• Gene: GABPA / 2551
• HGNCID: 4071
• Length: 454
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 109/399 - (27%)
• Similarity: 159/399 - (39%)
• Gaps: 106/399 - (26%)

  Fly    16 IISQTIRSAWCQQRPINAMHQDVRQ------KSIGSGNETKLEAKETEVPTNRRRRRRRCSSSST 74
            |:.||...|.|..:.|     |:.:      |.:....:..|:|.|.            |.....
Human    27 IVEQTYAPAECVSQAI-----DINEPIGNLKKLLEPRLQCSLDAHEI------------CLQDIQ 74

  Fly    75 SDSSASSYS---STDSDSGSSTSSSSIRSQLPALNLPVPLPLATP--TPPAVSSP--HQAPSPR- 131
            .|...|.:.   .||.....|....|.:...|.||:   |.:..|  |...|..|  |.|.|..
Human    75 LDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNI---LEIVKPADTVEVVIDPDAHHAESEAH 136

  Fly   132 ---------------------RNSSDSNRSVSPVE----------VPVDPHAWTPEDIASWVRWA 165
                                 ..|....|..:.:|          :|.||..|:.:.:..||.|.
Human   137 LVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWV 201

  Fly   166 TRKFKLDPEPDIDRFPKDAQELCDLSRADFWVCAGSRR--GGMLLAQHFAISLYHATGRETSPM- 227
            .::|.: .:.|:.......:|||.|::.||:     :|  .|.:|..|..:...:....:...|
Human   202 MKEFSM-TDIDLTTLNISGRELCSLNQEDFF-----QRVPRGEILWSHLELLRKYVLASQEQQMN 260

  Fly   228 ---------------LNDDEPNPYQLLNAASHRLVAQ-----------------GSGGQIQLWQF 260
                           :....|...:::|:::.....|                 |:.||||||||
Human   261 EIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAPRISGEDRSSPGNRTGNNGQIQLWQF 325

  Fly   261 LLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRYYYDKNIMTKV 325
            |||||.|....:.|||.|..|||:|..|:.||::||:||.||.|||:|||||||||||.:::.||
Human   326 LLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYYDGDMICKV 390

  Fly   326 HGKRYAYKF 334
            .|||:.|||
Human   391 QGKRFVYKF 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_523445.1	SAM_PNT	149..217	CDD:188876	18/69 (26%)
		ETS	254..339	CDD:197710	52/81 (64%)
GABPA	NP_002031.2	GABP-alpha	40..119	CDD:463311	18/98 (18%)
		SAM_PNT-GABP-alpha	168..254	CDD:176084	20/91 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316		1/18 (6%)
		ETS	319..403	CDD:197710	52/81 (64%)