DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets21C and Fev

DIOPT Version :9

Sequence 1:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_653354.2	Gene:	Fev / 246271	RGDID:	628860	Length:	237	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	101/228 - (44%)
Similarity:	115/228 - (50%)	Gaps:	77/228 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 VAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSR 311
            |.:|| |||||||||||||||.:||..|:|||..|||:|.|||||||||||||:|||||||||||
  Rat    40 VQKGS-GQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSR 103

  Fly   312 ALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPP 376
            |||||||||||:|||||||||:|||.||..|||                             |||
  Rat   104 ALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQ-----------------------------PPP 139

  Fly   377 LHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAP 441
            .|.|                                 :::.|::.|:..|..|...........|
  Rat   140 AHAH---------------------------------AAAAAAAAAAAAQDGALYKLPAGLAPLP 171

  Fly   442 FQG--------GTAGVDPARTSTSSAGNYDQGP 466
            |.|        .:|||.||..|      |..||
  Rat   172 FPGLSKLNLMAASAGVAPAGFS------YWPGP 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	71/84 (85%)
Fev	NP_653354.2	ETS	46..131	CDD:197710	71/84 (85%)
Fev	NP_653354.2	May mediate active transcriptional repression. /evidence=ECO:0000250	129..237		26/138 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1113327at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920