DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ets21C and ets-5

DIOPT Version :9

Sequence 1:	NP_001285547.1	Gene:	Ets21C / 33229	FlyBaseID:	FBgn0005660	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001263956.1	Gene:	ets-5 / 180778	WormBaseID:	WBGene00016600	Length:	246	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	99/199 - (49%)
Similarity:	123/199 - (61%)	Gaps:	30/199 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 LVAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLS 310
            |.|.|: |||||||||||||||:.||:.|:|||.:|||:|:|||||||:|||||:||||||||||
Worm    65 LSATGT-GQIQLWQFLLELLADAVNAHCIAWEGSNGEFKLVDPDEVARKWGERKSKPNMNYDKLS 128

  Fly   311 RALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQ--AQGGDP---ASSMLGSYNHHAGGAMQL 370
            |||||||||||||||.||||||||||.||..|||:.  ..||:|   .||.:.|.:.:....:.:
Worm   129 RALRYYYDKNIMTKVQGKRYAYKFDFQGLAQACQSAILTNGGNPNGDLSSTVHSLSPYTNQVLPI 193

  Fly   371 GRHPPPLHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSAST 435
            |                        :....|:..|:..|:...:|||:|:|..|.......|...
Worm   194 G------------------------VTSRLSTSMSSYHSILSSTSSTSSNQIIPPSTATYWSTPQ 234

  Fly   436 SNFT 439
            |:.|
Worm   235 SSLT 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_001285547.1	SAM_PNT	149..217	CDD:188876
Ets21C	NP_001285547.1	ETS	254..339	CDD:197710	71/84 (85%)
ets-5	NP_001263956.1	ETS	72..157	CDD:197710	71/84 (85%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167108
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3711
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.930