Protein Alignment Ets21C and Erg

DIOPT Version :10

• Sequence 1: NP_523445.1
• Gene: Ets21C / 33229
• FlyBaseID: FBgn0005660
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_598420.1
• Gene: Erg / 13876
• MGIID: 95415
• Length: 486
• Species: Mus musculus
• Alignment Length: 499
• Identity: 160/499 - (32%)
• Similarity: 209/499 - (41%)
• Gaps: 166/499 - (33%)

  Fly     9 QSHKQLPIISQTIRSAWCQQRPINAMHQDVRQKSIGSGNETKLEAKETEVPTNRRRRRRRCSSS- 72
            |:.|..|.:.|   ..|..|.|...              ..|:|...::| ...|.....||.:
Mouse    50 QTSKMSPRVPQ---QDWLSQAPARV--------------TIKMECNPSQV-NGSRNSPDECSVNK 96

  Fly    73 -----STSDSSASSYSSTDSDSGSSTSSSSIRSQLPALNLPVPLPLATPTPPAVSSPHQAPSPRR 132
                 .:.|:...||       ||......:                   ||    |:...:.||
Mouse    97 GGKMVGSPDTVGMSY-------GSYMEEKHV-------------------PP----PNMTTNERR 131

  Fly   133 NSSDSNRSVSPVEVPVDPHAWTPEDIASWVRWATRKFKLDPEPDIDRFPK-DAQELCDLSRADFW 196
                       |.||.||..|:.:.:..|:.||.:::.| .:.|:..|.. |.:|||.:::.||.
Mouse   132 -----------VIVPADPTLWSTDHVRQWLEWAVKEYGL-LDVDVLLFQNIDGKELCKMTKDDFQ 184

  Fly   197 VCAGSRRGGMLLAQ-HFA--------------------------------------ISLY-HATG 221
            ....|....:||:. |:.                                      .|:| .||.
Mouse   185 RLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQ 249

  Fly   222 RETS----------------------------------PMLNDDEP--NPYQLLNAASHRLVAQG 250
            |.|:                                  |...|..|  :|||:|...|.||...|
Mouse   250 RITTRPDLPYEPPRRSAWTGHSHLTPQSKAAQPSPSAVPKTEDQRPQLDPYQILGPTSSRLANPG 314

  Fly   251 SGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSRALRY 315
            | |||||||||||||:||||:|.|:|||.:|||::.|||||||||||||:|||||||||||||||
Mouse   315 S-GQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRY 378

  Fly   316 YYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSM---------LGSYNHHAGGAMQLG 371
            |||||||||||||||||||||||:..|.|..    .|.||:         :|||:.|......:.
Mouse   379 YYDKNIMTKVHGKRYAYKFDFHGIAQALQPH----PPESSLYKYPSDLPYMGSYHAHPQKMNFVS 439

  Fly   372 RHPPPLHHHPQHSHPHHQLGQPHF------LHPHHSSPASNSSS 409
            .|||.|   |..|........|::      ::|:...|||:..|
Mouse   440 PHPPAL---PVTSSSFFASPNPYWNSPTGGIYPNTRLPASHMPS 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ets21C	NP_523445.1	SAM_PNT	149..217	CDD:188876	20/107 (19%)
		ETS	254..339	CDD:197710	74/84 (88%)
Erg	NP_598420.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..62		4/14 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..99		4/20 (20%)
		SAM_superfamily	122..205	CDD:472832	26/98 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..311		11/61 (18%)
		ETS	317..400	CDD:197710	72/82 (88%)