Protein Alignment nAChRbeta3 and htr3b

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_021324909.1
• Gene: htr3b / 571632
• ZFINID: ZDB-GENE-071012-4
• Length: 369
• Species: Danio rerio
• Alignment Length: 356
• Identity: 93/356 - (26%)
• Similarity: 160/356 - (44%)
• Gaps: 51/356 - (14%)

  Fly    17 PLLLQMLMGMLLMGLTSVPGATATAD-PKNANVKALDRLHAGLFTNYDSDVQPVFQGT-PTNVSL 79
            |:||..|:      |:.:|.|....: ||.:.:..|.||   |...|:..|:||...| ||.:.:
Zfish     3 PVLLLSLL------LSVIPLAELVPEKPKRSALNQLTRL---LLRKYNCGVRPVQNWTKPTTIYI 58

  Fly    80 EMVV-TYIDIDELNGKLTTHCWLNLRWRDEERVWQPSQYDNITQITLKSSEVWTPQITLFN-GDE 142
            :::: ..:|:|....|:||..|....|.||..||.|.::|.||:|:|.|..:|.|.:.:.. .|.
Zfish    59 DLIIQAVLDVDGQTQKVTTSIWYRQIWNDEFLVWDPDEFDGITEISLSSDAIWVPDLIISEFVDV 123

  Fly   143 GGLMAETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSW-------GLKVVLPE 200
            |.......|.::..|..:...|....:.|.|.:..:|.|||:|.|...||       .|.:..|.
Zfish   124 GKSPVIPYVYVNCSGKVKNYKPIQVVSACHLEIYAFPFDKQNCTLTFRSWLHSVSEVDLALWRPA 188

  Fly   201 NGTARGESLDHDDLVQSPEWEI--VDSR---AHFVSQDYYGYMEYTLTAQRRSSMYTAVIYTPAS 260
            ...|.    |..:.:...|||:  |.||   .:...:| |..:::.:..:||..:|...:..|:.
Zfish   189 EEIAN----DTREFMNDGEWELLGVPSRYWTLNLEDRD-YAQIQFNVLIRRRPLLYVVGLLIPSI 248

  Fly   261 CIVILALSAFWLPPHMGGEKIMINGLLI--IVIAAFLMYFAQLLPVLSNNTPLVVIFYSTSLLYL 323
            .::::.:.:|:|||:.|........:|:  .||...||   ..:|..:..|||:.:|::..:..|
Zfish   249 FLMVVDVISFYLPPNSGTRITFKTSILLGYTVIRVNLM---DEIPATAIKTPLIGVFFAICMALL 310

  Fly   324 SVSTIVEVLVLYLATGKHKRRLPEALRKLLH 354
            .:|..:.:.|:                ||||
Zfish   311 LLSLAMSIFVV----------------KLLH 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	86/334 (26%)
		Neur_chan_LBD	52..247	CDD:280998	57/209 (27%)
		Neur_chan_memb	255..434	CDD:280999	23/102 (23%)
htr3b	XP_021324909.1	Neur_chan_LBD	26..>325	CDD:332142	82/325 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910