Protein Alignment nAChRbeta3 and chrna11

DIOPT Version :10

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001038562.1
• Gene: chrna11 / 566141
• ZFINID: ZDB-GENE-060503-606
• Length: 589
• Species: Danio rerio
• Alignment Length: 319
• Identity: 81/319 - (25%)
• Similarity: 157/319 - (49%)
• Gaps: 31/319 - (9%)

  Fly    58 LFTNYDSDVQPVFQGT-PTNVSLEM-VVTYIDIDELNGKLTTHCWLNLRWRDEERVWQPSQYDNI 120
            |..:|:...:||...: |..|.|.| ::..:|:||.|..|||:.|||:.|.|....|..|:|..:
Zfish    32 LLKDYNRMERPVANDSQPLTVFLSMSLIQIMDVDEKNQVLTTNIWLNMHWYDHYLQWNQSEYPGV 96

  Fly   121 TQITLKSSEVWTPQITLFNG--DEGGLMAETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQ 183
            ..:...:.:||||.|.|:|.  |:.....::.|.::..|:..::||.::.:.|.:::..:|.|.|
Zfish    97 KNLRFTTDQVWTPDILLYNSADDKFDSTFKSNVVVNSSGYCNYLPPGIFMSTCNVDVRWFPFDIQ 161

  Fly   184 SCKLKIGSW---GLKVVLPENGTARGESLDHDDLVQSPEWEIV------DSRAHFVSQDYYGYME 239
            .|:||.|||   |..:.|..|      ..|....:.:.||::|      :...:...::.|..:.
Zfish   162 KCELKFGSWTFDGWLLDLQMN------EADISGYMPNGEWDLVGVPGTRNELFYDCCKEPYPDVT 220

  Fly   240 YTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMINGLLIIVIAAFLMYFAQLLPV 304
            :.:|.:||:..|...:..|...:..:.|..|.||.. .||||.:...:::.:..|::..|:::|.
Zfish   221 FVVTIRRRTLYYALNLLIPCVLLSSMTLLIFLLPAD-SGEKISLGITVLLSLTVFMLLVAEIMPA 284

  Fly   305 LSNNTPLVVIFYSTSLLYLSVSTIVEVLVLYLATGKHKRRLPEALRKLLHGHLGTWLLL 363
            .|::.||:..::::.::.:.:|.|..|:||     ::....|..      |::..|:.|
Zfish   285 TSDSIPLIGQYFASIMIIVGMSVIATVVVL-----QYHHHDPNG------GNMPKWVQL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:455710	81/319 (25%)
chrna11	NP_001038562.1	LIC	2..577	CDD:455710	81/319 (25%)