Protein Alignment nAChRbeta3 and GluClalpha

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 96/441 - (21%)
• Similarity: 170/441 - (38%)
• Gaps: 84/441 - (19%)

  Fly    49 KALDR-LHAGLFTNYDSDVQPV-FQGT--PTNVSLEMVVTYID-IDELNGKLTTHCWLNLRWRDE 108
            |.||: |.||   .||:.::|. ..||  |..|.:.:.|..|. ||::..:.:.......:|.||
  Fly    35 KVLDQILGAG---KYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDE 96

  Fly   109 ERVWQPSQYDNITQITL-KSSEVWTPQITLFNGDEGG----LMAETQVTLSHDGHFRWMPPAVYT 168
            ...:...| ..:..:|| :::.||.|.:...|..||.    :|....:.:..:|...:......|
  Fly    97 RLKFDDIQ-GRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLT 160

  Fly   169 AYCELNMLNWPHDKQSCKLKIGSWGLK----VVLPENGTARGESLDHDDLVQS---PEWEIVDSR 226
            ..|.:|:..:|.|:|.|.|::.|:|..    |.|.:.|       |...:|::   |.:.:
  Fly   161 LACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEG-------DPVQVVKNLHLPRFTL---- 214

  Fly   227 AHFVSQDY---------YGYMEYTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIM 282
            ..|:: ||         |..::..|..:|..|.|...||.|...:||::..:|||.......::.
  Fly   215 EKFLT-DYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVS 278

  Fly   283 INGLLIIVIAAFLMYFAQLLPVLSNNTPLVVIFYSTSLLYLSVSTIVEVLVLYLA------TGKH 341
            :....::.:|.........||.:| .|..:.::....|.::..:.:...||.|.:      ...|
  Fly   279 LGVTTLLTMATQTSGINASLPPVS-YTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMH 342

  Fly   342 KRRLPEALRKLLHGHL------------GTWLLLSVFSTTGESQAEKTKEMDEHPYEEADEQESS 394
            |..:.:..|.|....|            .|:.:.|.|:..|..|    |.:..||        ..
  Fly   343 KENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQ----KPLVRHP--------GD 395

  Fly   395 PLGIN-------HTEVPG----AKANQFDWALLATAVDRISFVSFSLAFLI 434
            ||.:.       |.:.|.    .|.....:...:..:|.||.::|.|.|.:
  Fly   396 PLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFAL 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	96/441 (22%)
		Neur_chan_LBD	52..247	CDD:280998	50/220 (23%)
		Neur_chan_memb	255..434	CDD:280999	41/207 (20%)
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	96/441 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447346
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030