Protein Alignment nAChRbeta3 and CG8916

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 82/419 - (19%)
• Similarity: 146/419 - (34%)
• Gaps: 121/419 - (28%)

  Fly    39 ATADPKNANVKALDRLHAGLFTNYDSDVQPVF-QGTPTNVSLEMVVTYI-DIDELNGKLTTHCWL 101
            |.||..:.|:   ..:...|...|:....|.. ||.||.|...:::..: .:.||:...:..|:.
  Fly    99 AAADMLSRNI---SMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYF 160

  Fly   102 NLRWRDE------------------ERVWQPSQY------DNITQITLKSSEVWTPQITLFNGDE 142
            ...|||:                  :::|:|..|      ..|..||:       |...|.....
  Fly   161 RQYWRDKRLSFKGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITV-------PNKLLRLDQN 218

  Fly   143 GGLMAETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSWGLKVVLPENGTARGE 207
            ||::...::|:.              |.|.:.:.|:|.|:|||.|.|||:|
  Fly   219 GGILYSMRLTIK--------------ATCPMELQNFPMDRQSCPLVIGSYG-------------- 255

  Fly   208 SLDHDDLVQSPEWEIVDSRAHFV------SQDYYGYMEYTLTAQRRSSMYTAV------------ 254
             ..:..|:.  ||:..|....||      ..|....|....|..||...::.:
  Fly   256 -YINQQLIY--EWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGY 317

  Fly   255 ----IYTPASCIVILALSAFWLPPHMGGEKIMINGLLIIVIAAFLMYFAQLLPVLSNNTPLVVIF 315
                :|.|...||:|:..:||:......:::.:....::.::..         .|.:.|.|..:.
  Fly   318 FLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTI---------SLDSRTDLPKVK 373

  Fly   316 YSTSL--------LYLSVSTIVEVLVLYLATGKHKRRLPE--------ALRKLLHGHLGTWLLLS 364
            |:|:|        || .::|::|...::..|.......|:        .:...|..|.|.
  Fly   374 YATALDWFLLMSFLY-CIATLLEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGE----- 432

  Fly   365 VFSTTGESQAEKTKEMDEHPYEEADEQES 393
             ....||:.|:...:.|.....|.|:.|:
  Fly   433 -VDGDGEADADPFADEDSSNGSENDDNEA 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	82/419 (20%)
		Neur_chan_LBD	52..247	CDD:280998	47/226 (21%)
		Neur_chan_memb	255..434	CDD:280999	29/155 (19%)
CG8916	NP_573090.3	LIC	92..598	CDD:273305	82/419 (20%)
		Neur_chan_LBD	111..315	CDD:280998	49/241 (20%)
		Neur_chan_memb	322..>403	CDD:280999	17/90 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010