Protein Alignment nAChRbeta3 and acr-17

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001023961.1
• Gene: acr-17 / 191603
• WormBaseID: WBGene00000056
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 99/412 - (24%)
• Similarity: 170/412 - (41%)
• Gaps: 75/412 - (18%)

  Fly    18 LLLQMLMGMLLMGLTSVPGATATADPKNANVKALDRLHAGLFTNYDSDVQPVFQGT--PTNVSLE 80
            |||::::...||||       |.|..|        :|...||.:|..:::||...:  ||||:::
 Worm     6 LLLRIVVLHFLMGL-------AMAQQK--------QLIKYLFRDYHKELRPVKDESSGPTNVTVQ 55

  Fly    81 MVVTYID-IDELNGKLTTHCWLNLRWRDEERVWQPSQYDNITQITLKSSEVWTPQITLFNGDEGG 144
            :....|. :.|.:..:|.:||:...|:||...|.||.:.||..:.:.|..:|.|.:.::|.....
 Worm    56 LYFKQIQKVHENDQIITLYCWIEEYWQDEFLTWNPSDFGNIKSLHVPSEMIWKPDLLVYNNANMN 120

  Fly   145 LM---AETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSW---GLKVVLPE--- 200
            :.   .:|.|.:.|.|........:....|:|.|..:|:|:|.|.:.:.||   |.:::|..
 Worm   121 IKENEMQTNVQIEHTGKISLFRAIITDITCDLQMEKFPYDQQICFIMLASWSYDGSQIMLNTAEQ 185

  Fly   201 --------NGTARGESLDHDDLVQSPEWEIVDSRAHFVSQDY------YGYMEYTLTAQRRSSMY 251
                    ..|.....|:|  .:.:.||::||.|.....:.|      |..:.|....:|..|.|
 Worm   186 PTEAPLDIKNTTNLAILNH--YIPNMEWKLVDFRYRNNLKYYDCCPNPYPDISYFFAIKRNPSYY 248

  Fly   252 TAVIYTPASCIVILALSAFWLPPHMGG---EKIMINGLLIIVIAAFLMYFAQLLPVLSNNTPLVV 313
            ...:..|::.|.|:.:..|:.|....|   ||:.:....::.:|..||..:..||..||:.||:.
 Worm   249 LFTLIIPSAFITIVTVIGFFTPHSSTGENTEKVSLGVTALLSLAIILMMVSDKLPATSNSVPLLG 313

  Fly   314 IFYSTSLLYLSVSTIVEVLVLYLAT------------GKHKRRLPEALRKLL------HGHLGTW 360
            .:|           |..:.:::|||            |...|.:...||..|      ......|
 Worm   314 QYY-----------IGLIFIMFLATYCTTFTLGIQMQGNAGRPITRRLRSFLLSIRMNRNSFVQW 367

  Fly   361 LLLSVFSTTGESQAEKTKEMDE 382
            ........|.||...:.|:.|:
 Worm   368 FFGRELMNTQESIKMRLKKYDK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	92/391 (24%)
		Neur_chan_LBD	52..247	CDD:280998	53/220 (24%)
		Neur_chan_memb	255..434	CDD:280999	33/149 (22%)
acr-17	NP_001023961.1	LIC	23..491	CDD:273305	90/388 (23%)
		Neur_chan_LBD	24..245	CDD:280998	55/230 (24%)
		Neur_chan_memb	252..491	CDD:280999	33/149 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5722
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860