Protein Alignment nAChRbeta3 and acr-16

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_505207.1
• Gene: acr-16 / 179235
• WormBaseID: WBGene00000055
• Length: 498
• Species: Caenorhabditis elegans
• Alignment Length: 474
• Identity: 116/474 - (24%)
• Similarity: 192/474 - (40%)
• Gaps: 100/474 - (21%)

  Fly    53 RLHAGLFTNYDSDVQPVF-QGTPTNVSLEMVV-TYIDIDELNGKLTTHCWLNLRWRDEERVWQPS 115
            ||:..|..||::..:||. ...|..|.|::.: ..||:||.|..:..:.||:..|.|...||..:
 Worm    25 RLYEDLMRNYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWNDYNLVWDKA 89

  Fly   116 QYDNITQITLKSSEVWTPQITLFNGDEGGLMA--ETQVTLSHDGHFRWMPPAVYTAYCELNMLNW 178
            :|.|||.:...:.::|.|.:.|:|..:....:  :|.:.:...|...|:||.::...|::::..:
 Worm    90 EYGNITDVRFPAGKIWKPDVLLYNSVDTNFDSTYQTNMIVYSTGLVHWVPPGIFKISCKIDIQWF 154

  Fly   179 PHDKQSCKLKIGSW---GLKVVL-PENGTARGESLDHDDLVQSPEWEI----VDSRAHFVS--QD 233
            |.|:|.|..|.|||   |.|:.| |..|     ..|..:.:.:.||.:    |:....|..  .:
 Worm   155 PFDEQKCFFKFGSWTYDGYKLDLQPATG-----GFDISEYISNGEWALPLTTVERNEKFYDCCPE 214

  Fly   234 YYGYMEYTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMINGLLIIVIAAFLMYF 298
            .|..:.:.|..:||:..|...:..|.....::.|..|.|||. .||||.:...:::.|..||...
 Worm   215 PYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPD-AGEKITLQITVLLSICFFLSIV 278

  Fly   299 AQLLPVLSNNTPLVVIFYSTSLLYLSVSTIVEVLVLYLATGKHKRR-----------------LP 346
            :::.|..|...||:.||::..::.::.||:..|.||.|    |.|.                 :|
 Worm   279 SEMSPPTSEAVPLLGIFFTCCMIVVTASTVFTVYVLNL----HYRTPETHDMGPWTRNLLLYWIP 339

  Fly   347 EALRKLLHGHLGTWLLL-SVFSTT----GESQAEKTKEMDEHPYEEA------------------ 388
            ..||....||..|:..| |:|||.    .||.....|: :||....|
 Worm   340 WILRMKRPGHNLTYASLPSLFSTKPNRHSESLIRNIKD-NEHSLSRANSFDADCRLNQYIMTQSV 403

  Fly   389 ----------------------DEQESSPLGINH-----------TEVPGAKANQF--DWALLAT 418
                                  |..:.:.|.|.|           ..:.|.|..|.  :|...|.
 Worm   404 SNGLTSLGSIPSTMISSNGTTTDVSQQATLLILHRIYHELKIVTKRMIEGDKEEQACNNWKFAAM 468

  Fly   419 AVDRISFVSFSLAFLILAI 437
            .|||:....|::..::..|
 Worm   469 VVDRLCLYVFTIFIIVSTI 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	115/472 (24%)
		Neur_chan_LBD	52..247	CDD:280998	55/207 (27%)
		Neur_chan_memb	255..434	CDD:280999	57/253 (23%)
acr-16	NP_505207.1	LIC	6..493	CDD:273305	116/474 (24%)
		Neur_chan_LBD	23..229	CDD:280998	56/208 (27%)
		Neur_chan_memb	236..490	CDD:280999	58/258 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000891
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910