Protein Alignment nAChRbeta3 and chrne

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_002941867.4
• Gene: chrne / 100497712
• XenbaseID: XB-GENE-979686
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 454
• Identity: 112/454 - (24%)
• Similarity: 182/454 - (40%)
• Gaps: 96/454 - (21%)

  Fly    46 ANVKALDRLHAGLFTNYDSDVQP---VFQGTPTNVSLEMVVT-YIDIDELNGKLTTHCWLNLRWR 106
            ||.....||...|||||||..:|   :....|  |||::.:| .||::|....|||:.|:.:.|:
 Frog    19 ANESEESRLIKYLFTNYDSKARPSKGIDDVVP--VSLKLTLTNLIDLNEKEETLTTNVWVQIAWQ 81

  Fly   107 DEERVWQPSQYDNITQITLKSSEVWTPQITLFNGDEGGLMAE--TQVTLSHDGHFRWMPPAVYTA 169
            |:...|..::|..:..:.:....:|.|:|.|.|..:|.....  ..|.:...|:..|:|||::.:
 Frog    82 DDRLTWNETEYGGMPLVQVPHDMMWLPEIVLENNIDGNFEVAYYANVLVHSTGYIYWLPPAIFRS 146

  Fly   170 YCELNMLNWPHDKQSCKLKIGSWGLK--------VVLPENGTARGE-SLDHDDLVQSPEWEIVDS 225
            .|.:.:..:|.|.|:|.|...|....        |...|.|....: .:|.:...::.||.|:..
 Frog   147 TCSIEITYFPFDWQNCSLVFRSKTYSANDIDLHLVADDETGLPFDQVDIDREAFTENGEWAIMHR 211

  Fly   226 RAHFVSQDYYG-----YME--YTLTAQRRSSMYTAVIYTPASCIVILALSAFWLPPHMGGEKIMI 283
            .|..:....|.     |.|  :.|..||:...|...|..|...|..|.:..::||...||:|..:
 Frog   212 PARKIVNPKYSKEDLRYQEIVFILIIQRKPLFYIINIIVPCVLISSLVVLVYFLPAKAGGQKCTV 276

  Fly   284 NGLLIIVIAAFLMYFAQLLPVLSNNTPLV------VIFYSTSLLYLSVSTIVEVLV----LYLAT 338
            :..:::....||...||::|..|.:.||:      |:|.|| |:.||...::.|.:    .:..:
 Frog   277 SISVLLAQTVFLFLIAQMIPETSLSVPLIGKYLMFVMFVST-LIVLSCVIVLNVSLRSPSTHTLS 340

  Fly   339 GKHKRRLPEALRKLLHGHLGTWLLLSVFSTTGESQAEKTKEMDEHPYEEADEQESSPLGI----- 398
            .|.|..|.|.|.:.:|                 .:.|...|.:|.|    .|:..|.|||
 Frog   341 SKVKHMLLEVLPQFIH-----------------LRVEPCDEGEETP----RERRRSSLGIMLKAE 384

  Fly   399 ------------------NH---TEVPGAKANQFDWALLAT--------------AVDRISFVS 427
                              .|   .|..|.:|:.||..:..|              .||..:|::
 Frog   385 EYVLKKPRSELMFERQRERHGMRREPDGYRADGFDVGVTTTLYRNLAQCAPEIKDCVDACNFIT 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	112/454 (25%)
		Neur_chan_LBD	52..247	CDD:280998	58/216 (27%)
		Neur_chan_memb	255..434	CDD:280999	50/223 (22%)
chrne	XP_002941867.4	LGIC_ECD_nAChR_G	47..241	CDD:349830	49/195 (25%)
		Neur_chan_memb	248..491	CDD:397193	50/223 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910