Protein Alignment nAChRbeta3 and chrna9

DIOPT Version :9

• Sequence 1: NP_525098.1
• Gene: nAChRbeta3 / 33228
• FlyBaseID: FBgn0031261
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: XP_012811629.2
• Gene: chrna9 / 100493319
• XenbaseID: XB-GENE-983401
• Length: 494
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 126/509 - (24%)
• Similarity: 207/509 - (40%)
• Gaps: 118/509 - (23%)

  Fly    18 LLLQMLMGMLLMGLTSVPGATATADPKNANVKALDRLHAGLFTNYDSDVQPVFQGT--PTNVSLE 80
            ||..:.:.:.|.|:.|..|            |....|...||.:|.:.::|| :.|  ..||||:
 Frog    11 LLFHVFVLLDLKGVESAKG------------KYAQMLFRDLFEDYSNALRPV-EDTDKALNVSLQ 62

  Fly    81 MVVTYI-DIDELNGKLTTHCWLNLRWRDEERVWQPSQYDNITQITLKSSEVWTPQITLFN--GDE 142
            :.::.| |:||.|..||.:.|:.|.|.|....|...:||.:..|.:.|:.||.|.|.|:|  .||
 Frog    63 ITLSQIKDVDERNQILTAYLWIRLSWYDAYLKWDRDEYDGLDSIRIPSNMVWRPDIVLYNKADDE 127

  Fly   143 GGLMAETQVTLSHDGHFRWMPPAVYTAYCELNMLNWPHDKQSCKLKIGSWGLKVVLPENGTARG- 206
            ......|.|.|.:||...|..||:..:.|.:::..:|.|.|.|.|..|||          |..|
 Frog   128 FSEPVNTNVVLRYDGKITWDSPAITKSSCVVDVSYFPFDNQQCNLTFGSW----------TYNGN 182

  Fly   207 --------ESLDHDDLVQSPEWEIVDSRA------HFVSQDYYGYMEYTLTAQRRSSMYTAVIYT 257
                    :|.|..|.|::.|||:....|      :....:.|..:.:||..:||||.|...:..
 Frog   183 QVDIINTMDSGDLSDFVENVEWEMQGMPAVKNVITYGCCSEPYPDITFTLILKRRSSFYIFNLLI 247

  Fly   258 PASCIVILALSAFWLPPHMGGEKIMINGLLIIVIAAFLMYFAQLLPVLSNNTPLVVIFYSTSLLY 322
            |...|..||...|:||.. .|||:.:...:::.:..|.:..|:.:|. |.:.||:..:|..::..
 Frog   248 PCVMISFLAPLGFYLPAD-SGEKVSLGVTVLLALTVFQLMVAESMPP-SESVPLIGKYYIATMTM 310

  Fly   323 LSVSTIVEVLVLYL-ATGKHKRRLPEALRKLLHGHLGTWLLLSVFS-----TTGESQAEKTKEMD 381
            ::.||.:.::::.: ..|...:.:|...|.::..::..  :..|:.     |:.:|.:: ||...
 Frog   311 ITASTALTIIIMNIHLCGPEAKPIPRWARIVILDYMSK--IFFVYDVGENCTSPQSDSD-TKSNG 372

  Fly   382 EHPYEEADEQESSP---------------------------LG--------INHT---------- 401
            ..|..|..|:|..|                           ||        |:.|
 Frog   373 SVPSYEDYEKEQEPYSSLGCPLSGSGNFSCDIDTNKKLNGHLGGHYALQKEISETHCCAHCNRYR 437

  Fly   402 --------------EVPGAKANQFDWALLATAVDR-ISFVSFSLAF----LILA 436
                          |.....|...:|..:|..:|| ..:|.||:.|    ||:|
 Frog   438 VLTNNIEYITNWYREQKAISAKGIEWKKVAKVMDRFFMWVFFSMVFFMSILIIA 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta3	NP_525098.1	LIC	39..437	CDD:273305	120/488 (25%)
		Neur_chan_LBD	52..247	CDD:280998	65/214 (30%)
		Neur_chan_memb	255..434	CDD:280999	46/248 (19%)
chrna9	XP_012811629.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48230
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920