Protein Alignment Spp and Sppl2c

DIOPT Version :10

• Sequence 1: NP_523444.1
• Gene: Spp / 33227
• FlyBaseID: FBgn0031260
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_950184.2
• Gene: Sppl2c / 237958
• MGIID: 3045264
• Length: 690
• Species: Mus musculus
• Alignment Length: 285
• Identity: 76/285 - (26%)
• Similarity: 127/285 - (44%)
• Gaps: 57/285 - (20%)

  Fly    98 LYLFFKIFQKVHINYLLTGYFFVLGVIALAHLLSPVINSL--------MPAAVPKVPFHILFTKG 154
            ||.|:..|.     |::.|.|.:.....|...|:|::..|        :|.....|.:.:|...|
Mouse   279 LYFFYDCFV-----YVMIGIFSLGASTGLYSCLAPILCHLPLWRYQWVLPGQRVSVTWPLLLLAG 338

  Fly   155 EGKHKEDIVNYKFSTHDIVCLVISSAIGVWYLLKKH----WIANNLFGLAFAINGVEMLHLNNFV 215
                              :|.:::.   :|.:.:..    |:..:..|:|:.:..:..:.|..|.
Mouse   339 ------------------LCAMVTV---LWVIHRNEDHWAWLLQDTLGVAYCLFVLRRVRLPTFK 382

  Fly   216 TGVILLSGLFFYDIFWVF--------GTNVMVTVA------KSFE-APIKLVFPQDLIENGLNAS 265
            ...:.|..|..:|:|:||        |.::||.||      .|.| .|:.|..|: |..:.|...
Mouse   383 NCTLFLLALLAFDVFFVFITPLFTKTGESIMVEVASGPADSSSHERLPMVLKVPR-LSFSALTLC 446

  Fly   266 N--FAMLGLGDIVIPGIFIALLLRFDDSKKRKTRIYFYSTLIAYFLGLLATIFVMHVFKHAQPAL 328
            |  |::||.||||:||..:|...|| |.:.:..::|:.:..:||.:|||.|...|.:.:..||||
Mouse   447 NQPFSILGFGDIVVPGFLVAYCHRF-DMQVQSRQVYYMACTVAYAVGLLVTFVAMILMQMGQPAL 510

  Fly   329 LYLVPACMGTPLLVALIRGELKVLF 353
            ||||.:.:.|.|.||..|.|..:.:
Mouse   511 LYLVSSTLLTSLAVATCRQEFTLFW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spp	NP_523444.1	Peptidase_A22B	71..358	CDD:282158	76/285 (27%)
Sppl2c	NP_950184.2	PA	44..181	CDD:333703
		Peptidase_A22B	254..538	CDD:470165	76/285 (27%)
		PAL	508..510		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	564..633