DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lwr and ube2ka

DIOPT Version :9

Sequence 1:	NP_001259833.1	Gene:	lwr / 33226	FlyBaseID:	FBgn0010602	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_001013500.1	Gene:	ube2ka / 541355	ZFINID:	ZDB-GENE-050320-48	Length:	200	Species:	Danio rerio

Alignment Length:	163	Identity:	49/163 - (30%)
Similarity:	76/163 - (46%)	Gaps:	17/163 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGIAITRLGEERKAWRKDHPFGFVARPAKNP------DGTLNLMIWECAIPGKKSTPWEGGLYK 59
            |:.||:.|:..|.|...|..      ..:||.      |.....:..|  |.|...||:|||.|:
Zfish     1 MANIAVQRIKREFKEVLKSE------ETSKNQIKVDLVDENFTELRGE--IAGPPDTPYEGGRYQ 57

  Fly    60 LRMIFKDDYPTSPPKCKFEPPLFHPNVYP-SGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEP 123
            |.:...:.||.:|||.:|...::|||:.. :|.:||.:|  :..|..|:|::.:||.:|.||...
Zfish    58 LEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDIL--KGQWAAAMTLRTVLLSLQALLAAA 120

  Fly   124 NIKDPAQAEAYTIYCQNRLEYEKRVRAQARAMA 156
            ...||..|.....|.||...:::..|..:...|
Zfish   121 EPDDPQDAVVANQYKQNPEMFKQTARLWSHVCA 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lwr	NP_001259833.1	UQ_con	8..152	CDD:395127	45/150 (30%)
ube2ka	NP_001013500.1	COG5078	1..148	CDD:227410	48/156 (31%)
		UBCc	6..148	CDD:238117	45/151 (30%)
		UBA_like_SF	163..200	CDD:304366
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000