DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lwr and ube2ib

DIOPT Version :9

Sequence 1:	NP_001259833.1	Gene:	lwr / 33226	FlyBaseID:	FBgn0010602	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_571426.1	Gene:	ube2ib / 30622	ZFINID:	ZDB-GENE-990614-17	Length:	158	Species:	Danio rerio

Alignment Length:	153	Identity:	134/153 - (87%)
Similarity:	148/153 - (96%)	Gaps:	0/153 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSGIAITRLGEERKAWRKDHPFGFVARPAKNPDGTLNLMIWECAIPGKKSTPWEGGLYKLRMIFK 65
            |||||::||.:|||||||||||||||.|.||||||:|||.|||||||||.|||||||:||||:||
Zfish     1 MSGIALSRLAQERKAWRKDHPFGFVAVPMKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFK 65

  Fly    66 DDYPTSPPKCKFEPPLFHPNVYPSGTVCLSLLDEEKDWRPAITIKQILLGIQDLLNEPNIKDPAQ 130
            ||||:|||||||||||||||||||||||||:|:|:|||||||||||||||||:|||||||:||||
Zfish    66 DDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQ 130

  Fly   131 AEAYTIYCQNRLEYEKRVRAQAR 153
            |||||||||||:||||||||||:
Zfish   131 AEAYTIYCQNRVEYEKRVRAQAK 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lwr	NP_001259833.1	UQ_con	8..152	CDD:395127	127/143 (89%)
ube2ib	NP_571426.1	COG5078	1..156	CDD:227410	134/153 (88%)
		UQ_con	8..152	CDD:278603	127/143 (89%)
		Interaction with SUMO1. /evidence=ECO:0000250	13..18		4/4 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596148
Domainoid	1	1.000	284	1.000	Domainoid score	I1593
eggNOG	1	0.900	-	-		E2759_KOG0424
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2680
OMA	1	1.010	-	-		QHG53499
OrthoDB	1	1.010	-	-		D1522509at2759
OrthoFinder	1	1.000	-	-		FOG0002579
OrthoInspector	1	1.000	-	-		otm25521
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24067
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2323
SonicParanoid	1	1.000	-	-		X1694
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900