Protein Alignment ush and Zfpm1

DIOPT Version :10

• Sequence 1: NP_001259829.1
• Gene: ush / 33225
• FlyBaseID: FBgn0003963
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_038953934.1
• Gene: Zfpm1 / 691504
• RGDID: 1582810
• Length: 1001
• Species: Rattus norvegicus
• Alignment Length: 1307
• Identity: 265/1307 - (20%)
• Similarity: 389/1307 - (29%)
• Gaps: 554/1307 - (42%)

  Fly    75 EKANPQQ------DQDLGETEMEQE-HDLQQEDLQQELPA-NSPSTPPRSPSSPQLIPKLEQPAT 131
            :::||:|      |.:.||.....: ..::||....|.|| ..|.:|||...|   :|.:..|..
  Rat     5 KQSNPRQIKRSLRDMEAGEEAKGMDISPMEQEATAPEAPAIEEPPSPPREDVS---LPTVSAPPE 66

  Fly   132 PPSEPE-------------------------ASPCPSPSPCPT---------------------- 149
            .|.:||                         |||...|.....
  Rat    67 SPDDPEDVEGQELEMRPQDEKKEEKEEESAMASPWSGPEELELALQDGQRCVRARLSLTEGLSWG 131

  Fly   150 PKYPKVRLNALLAS----DPAL----------------------------KPDA----KELTLPD 178
            |.|..::..||...    .|||                            |.||    ....:|.
  Rat   132 PFYGSIQTRALSPEREEPGPALTLMVDESCWLRMLPQALTEEEANSEIYRKDDALWCRVTKAVPS 196

  Fly   179 SRLL-----APP------PLVKP-----------DTQAQPE-------VAEPLLKPARFMCLPCG 214
            ..||     |.|      |:.:|           |.|..|:       :|..::....|.|..||
  Rat   197 GGLLHVLLVAEPHGTPKHPVQEPEEAGSSGPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCG 261

  Fly   215 IAFSSPSTLEAHQAYYCSHR------IKDTDEAGSD--------------KSGAGGSGATAGDAA 259
            |.:.|...|:||..|||:.|      :..|:|...:              ||....|
  Rat   262 IWYRSERNLQAHLLYYCASRQRASSPVSATEEKPKETYPNERICPFPQCRKSCPSAS-------- 318

  Fly   260 GLTGGSTEPPAKMARTGKQYGCTQCSYSADKKVSLNRHMRMHQTSPAAPTLAGLPSLLQNGIAPP 324
                 |.|...:.....:.:.|..|..:...|.:..||:::|     ..||:..|:
  Rat   319 -----SLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVH-----TDTLSAWPT--------- 364

  Fly   325 GVTPNPMEDSSSQQTDRYCSHC-------DIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPG 382
            ||                |.:|       ||.::::.|    ....|.
  Rat   365 GV----------------CHNCGFISTTRDILYSHLVT----NHMVCQ----------------- 392

  Fly   383 AGSGPGSAGGSIGVSAQAATPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHS--HPPFLA 445
                |||.|       :..:||...|.|  |.|:.::...             ..||  |.|
  Rat   393 ----PGSKG-------EIYSPGAGHPAA--KLPSDSLTGF-------------QQHSLRHSP--- 428

  Fly   446 LPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALVGATLEP----- 505
                   :||..          ..|||:||:.:             |.||....|.|..|
  Rat   429 -------LVPAD----------KAPTPSSGLDS-------------KALAEVTNGETRVPPQNGG 463

  Fly   506 --ERPSAPSS----AAEATEA--KSSPPEPKRKEAGLTRESAPLDLSLRRSPITLNSLSLRQRQL 562
              |.|:||.:    |||..||  .|.|.||           .|...|...||.:.|.:.:
  Rat   464 SSESPAAPRTIKVEAAEEPEAARASGPGEP-----------GPQAPSRTPSPHSPNPVRV----- 512

  Fly   563 RNALLDVEEVLLAGVGTGKENVETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAG 627
                              |..:.:|..|.|..|.::..|.:|              ..|:.....
  Rat   513 ------------------KAELSSPTPGSSPGPGELTMAGTL--------------FLPQYVFGP 545

  Fly   628 SASSMSPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFP 692
            .|.:.:.|    |.|.              :..:|||.:..:..:|...      |||||.|..|
  Rat   546 DAGTTTVP----AAPQ--------------ASEILAKMSELVHNRLQQG------AGSSGVAGTP 586

  Fly   693 PASLPAQTSSGNPGSGGSAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQ--- 754
            ....|           |:.|             :.|.||.|.|....|:..||:.|||.|..
  Rat   587 TGLFP-----------GTKG-------------ATCFECEITFNNINNFYVHKRLYCSGRRAPED 627

  Fly   755 --------------------------------EGASEVDVKSAVSPSIAGAGGLGAGAAEAASSV 787
                                            .|..|.:...|.:|....||....|:....|||
  Rat   628 PPAVRRPKAATGSARAPAGVAAEPDPPRSSPGPGPREEEASGATTPEAETAGRGSEGSQSPGSSV 692

  Fly   788 ETTPVAYQQLICAACGIKYTSLDNLRAHQNYYC-------PKGGAVAAPAATPTDPGQLGMPKEK 845
            :.......:.:|.||.|:::..:....|:.|||       |:...|..||..|..|. |..|..:
  Rat   693 DDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPPVPTPAPGPAAPA-LTAPPVR 756

  Fly   846 CGKCKTLHEIGLP---CPPPVANPLAAPTV---------NPQPATNSLNKCPV--CGVV------ 890
            ..:.:.|:|  ||   .|||.|.|...|.|         :|:||:.|....|.  .|.|
  Rat   757 TRRRRKLYE--LPAAGAPPPAAGPAPVPVVSSPTAELPSSPRPASASAGPAPTPSPGPVPDGPID 819

  Fly   891 -----------SPTA--ALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNE 942
                       :|||  |||..|          .|:.|:...::|.....|      ||.|
  Rat   820 LSKRPRRQTPDTPTALPALADYH----------ECTACRVSFHSLEAYLAH------KKYS---- 864

  Fly   943 ELYMTCIFEEDASALSQELVTPTGASTTTGHDSMDHPSQMFNCDYCNYVSTYKGNVLRHMKLMHP 1007
                 |               |.....||.           .|.||......:|:::.|::..|
  Rat   865 -----C---------------PAAPLRTTA-----------LCPYCPPNGRVRGDLVEHLRQAH- 897

  Fly  1008 HVAINSPSISPDTRDQDVTSNPTTNQHSNSDVSNGEAPSFHIKSEPLDPPPTVNLVHENNNSPIA 1072
            .:.:..|:.||....:      |..:.:..|..:|.||.        .|.|          :|..
  Rat   898 GLQVAKPAASPGAEPR------TAAERAPRDSPDGRAPR--------SPSP----------APEN 938

  Fly  1073 TPHIKAEPIEVGADAAPGGLVPPMTSPLGNSSSVAAAAAAAAEVMKKYCSTCDISFNYVKTYLAH 1137
            ||..:|:.   ||..:..|...|..:|.|...             .:||..|:|.|:.:.|::||
  Rat   939 TPSDQADQ---GARTSCKGPPAPAPAPGGGGG-------------HRYCRLCNIRFSSLSTFIAH 987

  Fly  1138 KQFYCKN 1144
            |::||.:
  Rat   988 KKYYCSS 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ush	NP_001259829.1	zf-H2C2_5	279..301	CDD:404746	5/21 (24%)
		C2H2 Zn finger	884..904	CDD:275370	10/40 (25%)
		C2H2 Zn finger	912..932	CDD:275370	4/19 (21%)
		zf-H2C2_5	983..1003	CDD:404746	5/19 (26%)
Zfpm1	XP_038953934.1	PR-SET_ZFPM1	101..209	CDD:380992	15/107 (14%)
		C2H2 Zn finger	257..290	CDD:275368	12/32 (38%)
		C2H2 Zn finger	305..327	CDD:275368	5/34 (15%)
		C2H2 Zn finger	335..355	CDD:275368	5/19 (26%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)