Protein Alignment ush and zfpm1

DIOPT Version :9

• Sequence 1: NP_001259829.1
• Gene: ush / 33225
• FlyBaseID: FBgn0003963
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: NP_001034549.1
• Gene: zfpm1 / 407655
• ZFINID: ZDB-GENE-050419-238
• Length: 1191
• Species: Danio rerio
• Alignment Length: 1404
• Identity: 296/1404 - (21%)
• Similarity: 443/1404 - (31%)
• Gaps: 518/1404 - (36%)

  Fly    34 EQKQQQMEDQLEDQLNDSRDP---------QNNNNNIDDDADEDAEF---------EEPEKANPQ 80
            :.|.:|::..:.| ||...||         :...::.:|.|:.|...         |||......
Zfish     6 QSKPRQIKRSIGD-LNGGEDPSDDVSMSGEEGGASDQEDSAECDGSSPHSFTPLYNEEPRTHESL 69

  Fly    81 QDQDLGE---------TEMEQEHDLQQE--------------------------DLQQE------ 104
            ...|.||         ||.|:|.|:.:|                          ||..:
Zfish    70 AVSDEGEEDEKGLKRCTEDEEEEDVDREGEPQWNGPDDLVLSGSSDDFKVLALRDLSGDTVWGPF 134

  Fly   105 ---LPANSPSTPPRSPSSP-QLIPKLEQPATPPSEPEASPCPSPSPCPTPKYPKVRL-------- 157
               :.:..|:..|.|.||. .|:  .|:|.........:..|:.|.|.......|..
Zfish   135 SGSIQSGEPTDGPASESSAVSLV--CEEPDCWLRRIPVTSNPTDSNCTIYSQGGVLFCKLTRELS 197

  Fly   158 --NALLASDPALKPDAKELTLPDSRLL----APPPLVKPDTQAQPE-------VAEPLLKPARFM 209
              :|||||..:...|....|......:    |.|..:..:.|..|:       :|..::....|.
Zfish   198 GGDALLASLSSSNGDHSAGTQTHGVRVKEEPAYPAALHSEIQLLPQQAGMAAILATAVVNKDIFP 262

  Fly   210 CLPCGIAFSSPSTLEAHQAYYCSHRIKDTDEAGSDKSGAGGSGATAGDAAGLTGGSTEPPAKMAR 274
            |..|||.:.|...|:||..|||:.|.|....|                         .||....:
Zfish   263 CKDCGIWYRSERNLQAHLMYYCASRQKQQTAA-------------------------SPPQDKPK 302

  Fly   275 TG--KQYGC--TQCSYSADKKVSLNRHMRMHQTSPAAPTLAGLPSLLQNGIAPPGVTPNPMEDSS 335
            ..  .:..|  .||:.|.....||..|||.|........|..|.:.         .|....|...
Zfish   303 DSYPNERLCPFPQCNKSCPSASSLEIHMRTHSGERPFVCLICLSAF---------TTKANCERHL 358

  Fly   336 SQQTDR---YCSHC-------DIRFNNIKTYRAHKQHYCSSRRPEGQLTPK-PDASPGAGSGPGS 389
            ...||.   .|..|       ||.::::.|  :|.  .|.........:|| |.|   ||..||.
Zfish   359 KVHTDSLNGVCHGCGFISTTRDILYSHLVT--SHM--VCQPGSNSEVYSPKLPVA---AGLSPGD 416

  Fly   390 AGGSI-----GVSAQAATPGKLSPQARNKTPTPAMVAVAAAAAAAAASLQATPHSHPPFLALPTH 449
            :|..:     |.||.                |||::               ..|.|       ||
Zfish   417 SGIVLKCQVCGYSAD----------------TPALL---------------QQHVH-------TH 443

  Fly   450 PIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALVGATLEPERPSAPSSA 514
            ..:.||..  |:        |||                                  |.|:|.|:
Zfish   444 LEVRVPAE--RS--------PTP----------------------------------RQSSPPSS 464

  Fly   515 ----AEATEAKSSPPEPKRKEAGLTRESAPLDLSLRRSPITLNSLSLRQRQLRNALLDVEEVLLA 575
                .:.||..:..|.|.....|....||    |...||  |:.|::::....:...|.:|
Zfish   465 ELPELQETEPAACVPRPDSSSPGANGSSA----SQGYSP--LSQLNIKEEPRSDYENDAKE---- 519

  Fly   576 GVGTGKENVETPRGGGSVTPEQIVCAPSLPSSPSM--------SPSPKRRAISPRSSGAGSASSM 632
                 :|.|.:|:...:   |.....|:.|.||::        ||:|   ..||..||.|  .|:
Zfish   520 -----EEQVNSPQENAA---EASSSQPTSPKSPTVVAVKAEPASPTP---GSSPAHSGTG--GSV 571

  Fly   633 SPPGLNVAVPHLLDMRSMLPADFGLSESLLAKTNPELALKLAAAAAAAAVAGSSGAAA----FPP 693
            .|.|   ||        .||.....||:.:.....|:..|::....:....|...|||    :||
Zfish   572 LPGG---AV--------FLPQYMFNSEAAIMPQASEILAKMSEMVHSRLKQGQGPAAAQQSFYPP 625

  Fly   694 ASLPAQTSSGNPGSGGSAGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEG-- 756
                     |:|.|             |.||.: |.||:|.|....|:..||:.|||:|.|:|
Zfish   626 ---------GSPAS-------------VHKGAT-CFECDITFNNINNFYVHKRLYCSSRHQQGET 667

  Fly   757 ---------------------------------------------ASE---VDVK--------SA 765
                                                         |||   |:||        :.
Zfish   668 GGLVKEGAVTAAAPPASHAASPQARPVSRAASASPSCPDPAPGGTASEPKVVEVKIEDPGLKDAT 732

  Fly   766 VSPSIAGAGGLGAGAAEA----ASSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYC------ 820
            .|.|..|.|..|..|:|.    :.|.|.......:..|.||.|:::..||...|:.:||
Zfish   733 CSSSSEGEGPGGGQASEGSQSPSGSAEDQDDDPTRTFCQACNIRFSRHDNYIVHKRFYCASRHDP 797

  Fly   821 ----PKGGAVAAPAATPTDPGQLGMPKE-KCGKCKTLHEIGLPCPPPVANPLAAPT-----VNPQ 875
                |..|..|.            :|:. :..|.|.::||.:.....:||....|.     ||.:
Zfish   798 TNQRPHSGKAAF------------LPQPIRTRKRKKMYEIHMAQTEALANATTLPLGTSLGVNQE 850

  Fly   876 PATNSLNKCPVCGVVSPTAA----------LAK----KHMEMHGTVKA------YRCSICQYKGN 920
            .::.:|    :..|.:||.:          |:|    :..:...::.|      ::|:.|....|
Zfish   851 GSSVAL----LSQVSTPTRSSSPEGEGPIDLSKRPRLRESQRKDSISALPLSDYHKCTACSISFN 911

  Fly   921 TLRGMRTHIRTHFDKKTS---DVNEELYMTCIFEEDASAL---------SQELVTPTGASTTTGH 973
            ::.....| :|::...|:   ...|:|..   .:..||..         |...|..||.:....|
Zfish   912 SIENYLAH-KTYYCPATTLQPQTTEQLNR---LKRPASTSPKNRAVDQHSDSKVLQTGKTAAVAH 972

  Fly   974 ------DSMDH------------------PSQMFNCDYCNYVSTYKGNVLRHMKLMHPHVAIN-- 1012
                  .:..|                  |:::..||...:..|..|.||...:  ||.....
Zfish   973 AVPGSESTPPHVQGAKTPSTSPVVCPYCPPNKLLTCDLMEHFKTTHGLVLTLQQ--HPETQSTGV 1035

  Fly  1013 --SPSISPDTRDQDVTSNPTTNQHSNSDVSNGEAPSFHIKSEPLDP-PPTVN---LVHENNNSPI 1071
              |||:||  |:....:.|..:.....|..||.    .||.|...| ||.:|   |....:.||.
Zfish  1036 SPSPSLSP--REGAPLTPPKPSSRPRKDSLNGR----RIKLEATSPSPPVLNGSSLESVGSRSPK 1094

  Fly  1072 ATPHIKAEPIEVGADAAPGGL----------------------------VPPMT---SPLGNSSS 1105
            ..|. ...|..|.....|..|                            .||.|   |||.|.::
Zfish  1095 TAPP-ALSPKGVTVSPVPEALRETGQLSHTPLPTVLPEKAALAISHTHTAPPKTPLASPLQNGNT 1158

  Fly  1106 VAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKN 1144
                         :||..|:|.|:.:.|::|||::||.:
Zfish  1159 -------------RYCRLCNIKFSSLSTFIAHKKYYCSS 1184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ush	NP_001259829.1	C2H2 Zn finger	884..904	CDD:275370	5/33 (15%)
		C2H2 Zn finger	912..932	CDD:275370	4/19 (21%)
		zf-H2C2_5	983..1007	CDD:290620	6/23 (26%)
zfpm1	NP_001034549.1	C2H2 Zn finger	314..333	CDD:275368	8/18 (44%)
		zf-H2C2_2	325..350	CDD:290200	8/33 (24%)
		C2H2 Zn finger	341..361	CDD:275368	4/28 (14%)
		C2H2 Zn finger	369..386	CDD:275368	4/16 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576460
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003584
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.890