Protein Alignment ush and ush

DIOPT Version :10

• Sequence 1: NP_001259829.1
• Gene: ush / 33225
• FlyBaseID: FBgn0003963
• Length: 1212
• Species: Drosophila melanogaster
• Sequence 2: XP_061514367.1
• Gene: ush / 1280021
• VectorBaseID: AGAMI1_005268
• Length: 1493
• Species: Anopheles gambiae
• Alignment Length: 1505
• Identity: 527/1505 - (35%)
• Similarity: 686/1505 - (45%)
• Gaps: 456/1505 - (30%)

  Fly    34 EQKQQQMEDQLEDQLN-DSRDP--QNNNNNIDDDADEDAEFEEPEKANPQQDQDLGETE-MEQEH 94
            ||.|||.:.|...:.| ||...  .|:.|:....:...:......::|.:.:.:.|.|| .....
Mosquito    46 EQSQQQQQTQSTAEENGDSNSTIGSNSANSSSSSSSNSSGSNHSSRSNSRAEMNGGGTEGGGSAQ 110

  Fly    95 DLQQEDLQQELPA--NSPSTPPRSPS-------SPQLIPKLEQPATPPSEPEAS-----PCPSPS 145
            |.:....:.|:.|  ...::|.|:.:       :.:.:|..|....|.:|.||:     |..|.|
Mosquito   111 DTKPPCHETEMGAGERGSASPHRTATDERCETPADETMPLREIKQEPNAEQEAARHDHRPASSSS 175

  Fly   146 --------PCPTPKYPKVRLNALLASDPALKPDAKEL-TLPDSRLL------------------- 182
                    |.||| .|.:|||..||:|||..||||:| .|.|:...
Mosquito   176 SSHGAPHTPSPTP-MPMLRLNVALAADPAANPDAKDLKNLSDAEAALEEKQSQQLHQQQHALNMA 239

  Fly   183 ----APPPLVKPDTQAQP---------EVAEPLLKPAR---FMCLPCGIAFSSPSTLEAHQAYYC 231
                .|||.::....:.|         |:|.|:..|.|   |:|.||||.|||.|||||||.|||
Mosquito   240 IGGPPPPPALQQLASSTPPALLTRKPKELALPVELPPRLPMFICGPCGIRFSSASTLEAHQTYYC 304

  Fly   232 SHRIKDTDEAGSDKSGAGGSGAT--AGDAAGLTGGST---------------EPPAKMARTGKQY 279
            ||| ||.||.|....|..|:|.|  :|..|.:|||.:               :||||..:|||||
Mosquito   305 SHR-KDADEGGGGGGGGAGAGGTGNSGANATVTGGPSSGGVKNAHPGGEGGEQPPAKALKTGKQY 368

  Fly   280 GCTQCSYSADKKVSLNRHMRMHQTSPA-------------------------------------A 307
            .|:||||||||||||||||||||:||:                                     |
Mosquito   369 ACSQCSYSADKKVSLNRHMRMHQSSPSPSPVGAIVNGDEAIVLANHHQQQQQHQQQQQQLQLIQA 433

  Fly   308 PTLAGLPSLL------QNGIAPP-GVTPNPMEDSSSQQTDRYCSHCDIRFNNIKTYRAHKQHYCS 365
            ..:|...::|      |.|..|| |..|         |.|||||.|||||::.||||||||||||
Mosquito   434 QAVAAAAAVLHQQQQQQQGQQPPQGPAP---------QVDRYCSDCDIRFSSTKTYRAHKQHYCS 489

  Fly   366 SRRPEG----QLTPKPDASPGAGSGPGSAGGSIGVSAQAATPGKLSPQARNKTPTPAMVAVAAAA 426
            ||..||    ..||||.::|.:||                    .||....|||     .|.:||
Mosquito   490 SRHREGNQSNNSTPKPASAPKSGS--------------------QSPPDVPKTP-----PVGSAA 529

  Fly   427 AAAAASLQATPHSHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTI 491
            ||||:|.|       |||||||:|||::|.||||.||.|||.|.:...|:.|||:.||.:.||::
Mosquito   530 AAAASSQQ-------PFLALPTNPIIVIPYSLIRGASVIPGLLSSLAPGVANPESACFILQNGSL 587

  Fly   492 KPLATAL------VGATLEPE-------RPSAPS------SAAEATEAKSSPPEP---------- 527
            :|:|.:|      |.|.:.|.       .|..|:      |:....:....|.:|
Mosquito   588 QPIAMSLASQVQAVTAAIVPSGFEGLIGSPGGPATTRPGISSGNQQQTHQQPAQPPSRGPTPNIS 652

  Fly   528 ----------------------------KRKEAGLTRE----SAPLDLSLRR-SPITLNSLSLRQ 559
                                        .::|....|:    |.|||||:|| ||..:.|||||:
Mosquito   653 NSSDNNSVHSGSGGGGPASGTGEVLKAINKRENSANRDAPTGSTPLDLSVRRLSPGAIGSLSLRE 717

  Fly   560 RQL-------RNALLDVEEVLLAGVGTGKENVETPRGGGSVTPEQIVCAPSLPSSPSMSPSPKRR 617
            |.|       .:..||.:.::     .||||:..  .|.|:||||||||||||.||.::||||||
Mosquito   718 RSLSLSSAVSADPRLDFDSLM-----EGKENLSV--SGDSLTPEQIVCAPSLPGSPPLTPSPKRR 775

  Fly   618 AISPRSSGAG----------------------SASSMSPPGLNVAV------PHLLD---MRSML 651
            :.|||..|.|                      :|::.|..||...|      |..|.   ||.:|
Mosquito   776 SNSPRGGGGGGGGVPPPVSNATTAAAVAAAAHAAAAASQHGLGGPVGGLSLSPLTLQQQLMRPLL 840

  Fly   652 PADFGL-------------------SESLLAKTNPELALKLAAAAAAAAVAGSSGAAAFPPAS-- 695
            |||..|                   :..||.|.:.||||:|   :::|.|....|..|.|..|
Mosquito   841 PADIALRLSAVGDPGVNLNLNILPNTHPLLTKQSVELALRL---SSSAGVPVGDGGLAKPQISPL 902

  Fly   696 LPAQTSSGNPGSGGS-----AGGAQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQE 755
            |.:.:.:|:.|.||.     |..||.|||:||:|.|||.||||||||||||||||:||||||:|:
Mosquito   903 LNSISPTGSVGGGGPAAAVLAAAAQTPQIFVKQGDSKCKECNIVFCKYENYLAHKKHYCSARNQD 967

  Fly   756 GASEVD---VKSAVSP-SIAGAGGLGAGAAEAAS----SVETTPVAYQQLICAACGIKYTSLDNL 812
            |..:.:   |...:|| ::.|.||.|||....:|    ::....||||||||||||||:||||||
Mosquito   968 GGGDGELPKVSPPISPQAMGGGGGGGAGGGGVSSGGSPAIGVGAVAYQQLICAACGIKFTSLDNL 1032

  Fly   813 RAHQNYYCPKGGAVAAPAATPTDPGQLGMP-KEKCGKCKTLHEIGLPCPPPVANPLAAPTVNPQP 876
            .|||.|||||......|.:..|.......| ||:|.|||:|||.|.||           ||
Mosquito  1033 SAHQMYYCPKRIDATLPVSATTTTVVTAQPHKERCSKCKSLHEPGQPC-----------TV---- 1082

  Fly   877 ATNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVN 941
            |.:...|||:|.|:||.:..|::||:.||.|||:||:||:||||||||||||||.|||||||:.|
Mosquito  1083 AGHGAYKCPICEVISPNSTEARRHMDTHGGVKAFRCTICRYKGNTLRGMRTHIRMHFDKKTSEFN 1147

  Fly   942 EELYMTCIFEED-----------------------ASAL-SQELVTPTGASTTTGHDSMDHP--- 979
            ||.::|||.|||                       |.|| ||:...|...|...|...:..|
Mosquito  1148 EENFITCILEEDGIEIPPAGAQNAAAMAAAAAAAAAHALASQKSFAPPPPSEADGMARISPPTAG 1212

  Fly   980 ---SQMFNCDYCNYVSTYKGNVLRHMKLMH----------------------------------- 1006
               |...:|::|.|.|:|:.||.:|:|.:|
Mosquito  1213 NGQSVRHHCEFCPYSSSYRVNVAKHIKHVHGRDGPSPGSSPLIGEGGESLLYNGTGPVAGDSGSV 1277

  Fly  1007 ---PHVAI-------NSPSI------------SPDTRDQ-DVTSNPTTNQHSNSDVSNGEAPSFH 1048
               |.:|:       ||..|            |||..|. |:          |.|:...|.|:
Mosquito  1278 IARPPIAVTPGLTMANSQVIKTEPKDEAGHAPSPDAPDALDI----------NVDIVLEEPPA-- 1330

  Fly  1049 IKSEPLDP-PPTVNLVHENNNSPIATPHIKAEPIEVGADAA-PGGLVPPMTSPLGNSSS------ 1105
            ||||..|| .|::       |||:.:|...:.|....|.|| |...|...:.|...:||
Mosquito  1331 IKSEVFDPHMPSL-------NSPLTSPVTPSPPAAAAAPAAVPSTTVKQKSHPTNAASSPGGRTE 1388

  Fly  1106 -----------VAAAAAAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEASDSPSPNH 1159
                       |:|..:.......|||.||||:|||..||:|||:||||.......|:.:.:...
Mosquito  1389 HGIKTPSPPVEVSAGGSPQLPPGPKYCDTCDITFNYTNTYIAHKKFYCKAAVAAAAAAAAAAAGT 1453

  Fly  1160 LGGGVAVGLG 1169
            .......|:|
Mosquito  1454 ASASAGSGVG 1463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ush	NP_001259829.1	zf-H2C2_5	279..301	CDD:404746	19/21 (90%)
		C2H2 Zn finger	884..904	CDD:275370	9/19 (47%)
		C2H2 Zn finger	912..932	CDD:275370	17/19 (89%)
		zf-H2C2_5	983..1003	CDD:404746	8/19 (42%)
ush	XP_061514367.1	None