Protein Alignment cbt and COM2

DIOPT Version :10

• Sequence 1: NP_722636.1
• Gene: cbt / 33224
• FlyBaseID: FBgn0043364
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_011056.1
• Gene: COM2 / 856867
• SGDID: S000000932
• Length: 443
• Species: Saccharomyces cerevisiae
• Alignment Length: 371
• Identity: 88/371 - (23%)
• Similarity: 138/371 - (37%)
• Gaps: 104/371 - (28%)

  Fly    18 ENKLEIVAKDEQQVNENLLKAKLKLVAQKSQKNGGIITPNPSDTEDEAPEIAVPNKKPRLEQPAM 82
            |:.:.:|:.||.:|||       :....|.|...|:            ..|:..|....||....
Yeast   131 ESDVLMVSDDELEVNE-------RFSFLKQQPLDGL------------NRISSTNNLKNLEIHEF 176

  Fly    83 SMTPPP--DQKLDDD-----QKAERVSVIMRVNSSGAVSSSSQDENSSSSTSCCSSSSNTNTSTS 140
            .:.|..  |.:|:|.     |..::|....::|..|:                 |||||.|:::.
Yeast   177 IIDPTENIDDELEDSFTTVPQSKKKVRDYFKLNIFGS-----------------SSSSNNNSNSL 224

  Fly   141 SVPPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPPAPAECIKEEEIKPIL 205
            ...|...::.....:::| :|..:||.....:||..|..|..:.......:..|  .:|....|:
Yeast   225 GCEPIQTENSSSQKMFKN-RFFRSRKSTLIKSLPLEQENEVLINSGFDVSSNEE--SDESDHAII 286

  Fly   206 TPI----------------------------YVSPVA--SSASQLILLSTVA-AQQSPTPVPKTP 239
            .|:                            .:.||:  |:.|:..||:.:: ...||:|...:|
Yeast   287 NPLKLVGNNKDISTQSIAKTTNPFKSGSDFKMIEPVSKFSNDSRKDLLAAISEPSSSPSPSAPSP 351

  Fly   240 TM----SEEKLTTRITAAQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENC 300
            ::    |...|..|........||.| .....||..|.                   |.|  |.|
Yeast   352 SVQSSSSSHGLVVRKKTGSMQKTRGR-KPSLIPDASKQ-------------------FGC--EFC 394

  Fly   301 DKRFSRSDELSRHKRT-HTGEKKFQCSVCQKKFMRSDHLSKHVKRH 345
            |:||.|.:.|.||.|: |..||.|.|.:|.|.|.|||:|::|||.|
Yeast   395 DRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTH 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	C2H2 Zn finger	265..287	CDD:275368	3/21 (14%)
		COG5048	<270..362	CDD:227381	29/77 (38%)
		C2H2 Zn finger	295..317	CDD:275368	11/22 (50%)
		zf-H2C2_2	309..332	CDD:463886	11/23 (48%)
		C2H2 Zn finger	325..345	CDD:275368	11/19 (58%)
COM2	NP_011056.1	COG5048	1..443	CDD:227381	88/371 (24%)
		C2H2 Zn finger	391..412	CDD:275368	11/22 (50%)
		C2H2 Zn finger	420..440	CDD:275368	11/19 (58%)