Protein Alignment cbt and CRZ1

DIOPT Version :10

• Sequence 1: NP_722636.1
• Gene: cbt / 33224
• FlyBaseID: FBgn0043364
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_014371.1
• Gene: CRZ1 / 855704
• SGDID: S000004972
• Length: 678
• Species: Saccharomyces cerevisiae
• Alignment Length: 415
• Identity: 94/415 - (22%)
• Similarity: 148/415 - (35%)
• Gaps: 130/415 - (31%)

  Fly    32 NENLLKAKLKLVAQKSQKNGGIITPNPSDTEDEAPEIAVPNKKPRLEQPAMSMTPPPDQKLDDDQ 96
            :.|||.|...  :..:..|.|||  |.:||::..  ||:...|....| .|.:|.|.........
Yeast   267 DNNLLSASNN--SDFNNSNNGII--NTADTQNST--IAINKSKVGTNQ-KMLLTIPTSSTPSPST 324

  Fly    97 KAERVSVIMRV------------NSSGAVSSSSQDENSSSSTSCCSSSSN---------TNTSTS 140
            .|..|:.|:.:            ...|.:....:|..|.|:|    :::|         .|.:.|
Yeast   325 HAAPVTPIISIQEFNEGHFPVKNEDDGTLQLKVRDNESYSAT----NNNNLLRPDDNDYNNEALS 385

  Fly   141 SVPPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPPAPAECIKEEEIK--- 202
            .:..:.||...    .|.||.|.:|:|:::.:.....:..:..::.::|...|:.|.....|
Yeast   386 DIDRSFEDIIN----GRKLKLKKSRRRSSQTSNNSFTSRRSSRSRSISPDEKAKSISANREKLLE 446

  Fly   203 ----------------------------------------PILT--PIYVSPVASSASQL----- 220
                                                    .:||  |...|.:.:..::|
Yeast   447 MADLLPSSENDNNRERYDNDSKTSYNTINSSNFNEDNNNNNLLTSKPKIESGIVNIKNELDDTSK 511

  Fly   221 ---ILLSTVAAQQ------------------SPTPVPKTPTMSEEKLTTRITAAQAAATRSRIYE 264
               |||...:..|                  ....|.|...:  |||.        :.|.:|...
Yeast   512 DLGILLDIDSLGQFEQKVGFKNDDNHENNDNGTFSVKKNDNL--EKLD--------SVTNNRKNP 566

  Fly   265 CSF--PDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTGEKKFQCS- 326
            .:|  ..|||.:.:..:||:|.|.||.||||||  ..|.|.|:|..:..||:..|||:|::.|.
Yeast   567 ANFACDVCGKKFTRPYNLKSHLRTHTNERPFIC--SICGKAFARQHDRKRHEDLHTGKKRYVCGG 629

  Fly   327 --------VCQKKFMRSDHLSKHVK 343
                    .|.|||.|||.|.:|.|
Yeast   630 KLKDGKPWGCGKKFARSDALGRHFK 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	C2H2 Zn finger	265..287	CDD:275368	8/23 (35%)
		COG5048	<270..362	CDD:227381	36/83 (43%)
		C2H2 Zn finger	295..317	CDD:275368	7/21 (33%)
		zf-H2C2_2	309..332	CDD:463886	9/31 (29%)
		C2H2 Zn finger	325..345	CDD:275368	11/28 (39%)
CRZ1	NP_014371.1	COG5048	139..617	CDD:227381	79/376 (21%)
		C2H2 Zn finger	571..591	CDD:275368	7/19 (37%)
		Zn_ribbon_recom	598..656	CDD:433183	23/59 (39%)
		C2H2 Zn finger	599..619	CDD:275368	7/21 (33%)
		C2H2 Zn finger	627..655	CDD:275368	11/28 (39%)