DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cbt and FZF1

DIOPT Version :9

Sequence 1:	NP_722636.1	Gene:	cbt / 33224	FlyBaseID:	FBgn0043364	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_011260.1	Gene:	FZF1 / 852638	SGDID:	S000003223	Length:	299	Species:	Saccharomyces cerevisiae

Alignment Length:	173	Identity:	53/173 - (30%)
Similarity:	76/173 - (43%)	Gaps:	24/173 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 TRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTGEKK 322
            |:||.|:|||..|.|.|.:.|.|:.||..||.::|:.|....|.|:|.|...|..||.||:..|.
Yeast     7 TKSRNYKCSFDGCEKVYNRPSLLQQHQNSHTNQKPYHCDEPGCGKKFIRPCHLRVHKWTHSQIKP 71

  Fly   323 FQCSVCQKKFMRSDHLSKHVKRHNKD---------KANGVNRHVSLANNNTSASVAASLCDASLH 378
            ..|::|||:|:.:..|.:|:..|.:.         |..|||.:|....|.........|
Yeast    72 KACTLCQKRFVTNQQLRRHLNSHERKSKLASRIDRKHEGVNANVKAELNGKEGGFDPKL------ 130

  Fly   379 LRAIAPAGSSASSSPISSASLQVYSAQDLLRLQ----QQASSF 417
                 |:||.......|...|..|....:|:..    |:.:||
Yeast   131 -----PSGSPMCGEEFSQGHLPGYDDMQVLQCPYKSCQKVTSF 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	zf-C2H2	263..287	CDD:278523	11/23 (48%)
		C2H2 Zn finger	265..287	CDD:275368	10/21 (48%)
		COG5048	<270..362	CDD:227381	34/100 (34%)
		zf-H2C2_2	279..306	CDD:290200	10/26 (38%)
		C2H2 Zn finger	295..317	CDD:275368	8/21 (38%)
		zf-H2C2_2	309..332	CDD:290200	10/22 (45%)
		zf-C2H2	323..345	CDD:278523	7/21 (33%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
FZF1	NP_011260.1	COG5048	15..297	CDD:227381	48/165 (29%)
		C2H2 Zn finger	17..36	CDD:275368	7/18 (39%)
		C2H2 Zn finger	44..66	CDD:275368	8/21 (38%)
		C2H2 Zn finger	74..94	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.900