DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cbt and klf9

DIOPT Version :9

Sequence 1:	NP_722636.1	Gene:	cbt / 33224	FlyBaseID:	FBgn0043364	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001122201.1	Gene:	klf9 / 565869	ZFINID:	ZDB-GENE-060526-244	Length:	216	Species:	Danio rerio

Alignment Length:	192	Identity:	79/192 - (41%)
Similarity:	105/192 - (54%)	Gaps:	16/192 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 EEIKPILTPIYVSPVASSASQLILLSTVAAQQSPTPVPKTPTMSEEKLTTRITAAQAAATRSR-- 261
            ||.:...|.:.|:.:....:|.| .|.::|::.   |.......|.:...:.||.:...||.|
Zfish    30 EESQESRTLLMVAMILLDLNQCI-PSGISAKRI---VDSDAENRENREKCKQTAGRVKRTRKRDR 90

  Fly   262 -------IYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTG 319
                   .:.|.:..|||.|.||||||||.|||||||||.|.|..|.|:|||||||:||.|||||
Zfish    91 LHASAEKRHCCPYAGCGKIYGKSSHLKAHFRVHTGERPFQCTWPGCAKKFSRSDELTRHFRTHTG 155

  Fly   320 EKKFQCSVCQKKFMRSDHLSKHVKRHNKDKANGVNRHVSLANNNTSASVAASLCDASLHLRA 381
            ||:|.|.:|.|.|||||||:||.:||.....:.:..|   |.....:|.:.|...:|.|:.|
Zfish   156 EKRFMCPLCDKCFMRSDHLTKHARRHAGFHPSMLQGH---AGRRRHSSTSTSSSGSSDHMSA 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	zf-C2H2	263..287	CDD:278523	14/23 (61%)
		C2H2 Zn finger	265..287	CDD:275368	14/21 (67%)
		COG5048	<270..362	CDD:227381	58/91 (64%)
		zf-H2C2_2	279..306	CDD:290200	19/26 (73%)
		C2H2 Zn finger	295..317	CDD:275368	14/21 (67%)
		zf-H2C2_2	309..332	CDD:290200	15/22 (68%)
		zf-C2H2	323..345	CDD:278523	13/21 (62%)
		C2H2 Zn finger	325..345	CDD:275368	12/19 (63%)
klf9	NP_001122201.1	C2H2 Zn finger	101..123	CDD:275368	14/21 (67%)
		COG5048	113..>161	CDD:227381	37/47 (79%)
		C2H2 Zn finger	131..153	CDD:275368	14/21 (67%)
		zf-H2C2_2	145..168	CDD:290200	15/22 (68%)
		zf-C2H2	159..181	CDD:278523	13/21 (62%)
		C2H2 Zn finger	161..181	CDD:275368	12/19 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910