DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cbt and odd-1

DIOPT Version :9

Sequence 1:	NP_722636.1	Gene:	cbt / 33224	FlyBaseID:	FBgn0043364	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_498552.2	Gene:	odd-1 / 181893	WormBaseID:	WBGene00003845	Length:	242	Species:	Caenorhabditis elegans

Alignment Length:	276	Identity:	62/276 - (22%)
Similarity:	103/276 - (37%)	Gaps:	91/276 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 SMTPPPDQKLDD-------DQKAERVSVIMRVNSSGAVSSSSQDENSSSSTSCCSSSSN---TNT 137
            |..||....::|       .|:...:..:::..|...|:.:|.|..:..::.|.|.||:   :|.
Worm    11 STVPPVVPSVEDIIRMLVAGQQKIAIQNLLQSQSKEQVNGTSHDLQNWLTSLCISPSSSPTPSNA 75

  Fly   138 STSSVPPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPPAPAECIKEEEIK 202
            |||::|..:.::    ||..                  :|                  |:.:...
Worm    76 STSTIPAQMTNE----NVLH------------------LQ------------------IQSQLFS 100

  Fly   203 PILTPIYVSPVASSASQLILLSTVAAQQSPT--PVPKTPTMSEEKLTTRITAAQAAATRSRIYEC 265
            .:.||.:::|               .|.:.|  .:.|.|                    .:.:.|
Worm   101 NLGTPWFLNP---------------EQHNKTNNAIRKRP--------------------KKEFIC 130

  Fly   266 SFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTHTGEKKFQCSVCQK 330
            .:  |.:::.||.:|..|:|.||.||||.|  |.|.|.|.|.|.|..||..|..||..:|.:|.|
Worm   131 KY--CARHFTKSYNLMIHERTHTNERPFHC--ETCGKSFRRQDHLRDHKYIHAKEKPHKCEICGK 191

  Fly   331 KFMRSDHLSKHVKRHN 346
            .|.:...|:.|...|:
Worm   192 GFCQLRTLNVHRSCHH 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	zf-C2H2	263..287	CDD:278523	7/23 (30%)
		C2H2 Zn finger	265..287	CDD:275368	7/21 (33%)
		COG5048	<270..362	CDD:227381	32/77 (42%)
		zf-H2C2_2	279..306	CDD:290200	14/26 (54%)
		C2H2 Zn finger	295..317	CDD:275368	10/21 (48%)
		zf-H2C2_2	309..332	CDD:290200	9/22 (41%)
		zf-C2H2	323..345	CDD:278523	6/21 (29%)
		C2H2 Zn finger	325..345	CDD:275368	6/19 (32%)
odd-1	NP_498552.2	C2H2 Zn finger	130..150	CDD:275368	7/21 (33%)
		zf-H2C2_2	142..167	CDD:290200	14/26 (54%)
		C2H2 Zn finger	158..178	CDD:275368	10/21 (48%)
		zf-H2C2_2	170..193	CDD:290200	9/22 (41%)
		C2H2 Zn finger	186..206	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030