Protein Alignment cbt and Klf5

DIOPT Version :10

• Sequence 1: NP_722636.1
• Gene: cbt / 33224
• FlyBaseID: FBgn0043364
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_033899.2
• Gene: Klf5 / 12224
• MGIID: 1338056
• Length: 446
• Species: Mus musculus
• Alignment Length: 353
• Identity: 105/353 - (29%)
• Similarity: 148/353 - (41%)
• Gaps: 85/353 - (24%)

  Fly     5 TLLPSPPATPPLRENKLEIVAKDE-----QQVNENLLKAKLKLVAQKSQKNGGIITPNPSDTEDE 64
            |..|.|||..........|.:..:     |:||...:|.:|               |.|.
Mouse   165 TAPPPPPAPTQALPEFTSIFSSHQTTAPPQEVNNIFIKQEL---------------PIPD----- 209

  Fly    65 APEIAVPNKKPRLEQPAMSMTPPPDQKLDDDQKAERVSVIMRVNSSGAVSSSSQDENSSSSTSCC 129
             ..::||:::..|.|    :...||  ||......:.:|:..:|.|.|
Mouse   210 -LHLSVPSQQGHLYQ----LLNTPD--LDMPSSTNQTAVMDTLNVSMA----------------- 250

  Fly   130 SSSSNTNTSTSSVPPTVEDDY---PEANVWRNLKFKMNRKRAAEVALPPVQT---PETPVAKLVT 188
                ..|...|:||.|....:   |........:|           ||...|   |..|.::..:
Mouse   251 ----GLNPHPSAVPQTSMKQFQGMPPCTYTMPSQF-----------LPQQATYFPPSPPSSEPGS 300

  Fly   189 PPAPAECIKEEEIKPILTPIYVSPVASSASQLILLSTVAAQQSPTPVP-KTPTMSEEKLTTRITA 252
            |...||.:  :.:.|  .|.|.:.:||..:       :.....|..:| .:||:...:...|
Mouse   301 PDRQAEML--QNLTP--PPSYAATIASKLA-------IHNPNLPATLPVNSPTLPPVRYNRR--- 351

  Fly   253 AQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHKRTH 317
            :.....:.||:.|.:..|.|.|.||||||||.|.||||:|:.|.||.||.||:|||||:||.|.|
Mouse   352 SNPDLEKRRIHFCDYNGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKH 416

  Fly   318 TGEKKFQCSVCQKKFMRSDHLSKHVKRH 345
            ||.|.|||.|||:.|.|||||:.|:|||
Mouse   417 TGAKPFQCMVCQRSFSRSDHLALHMKRH 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	C2H2 Zn finger	265..287	CDD:275368	13/21 (62%)
		COG5048	<270..362	CDD:227381	52/76 (68%)
		C2H2 Zn finger	295..317	CDD:275368	15/21 (71%)
		zf-H2C2_2	309..332	CDD:463886	15/22 (68%)
		C2H2 Zn finger	325..345	CDD:275368	12/19 (63%)
Klf5	NP_033899.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		KLF5_N	3..359	CDD:410335	50/266 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69
		9aaTAD. /evidence=ECO:0000250|UniProtKB:Q13887	107..115
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..310		6/27 (22%)
		Interaction with WWP1. /evidence=ECO:0000250	313..317		2/5 (40%)
		COG5048	338..>422	CDD:227381	42/86 (49%)
		C2H2 Zn finger	367..386	CDD:275368	12/18 (67%)
		C2H2 Zn finger	394..416	CDD:275368	15/21 (71%)
		zf-H2C2_2	408..433	CDD:463886	16/24 (67%)
		C2H2 Zn finger	424..444	CDD:275368	12/19 (63%)