DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cbt and Klf9

DIOPT Version :9

Sequence 1:	NP_722636.1	Gene:	cbt / 33224	FlyBaseID:	FBgn0043364	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_476559.2	Gene:	Klf9 / 117560	RGDID:	70934	Length:	244	Species:	Rattus norvegicus

Alignment Length:	185	Identity:	76/185 - (41%)
Similarity:	102/185 - (55%)	Gaps:	28/185 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 PVQTPETPVAKLVTPP----APAECIKEEEIKPILTPIYVSPVASSASQLILLSTVAAQQSPTPV 235
            |:|||......|.:|.    :.::...|....|..:|.......|:.|.|.||.:..|.
  Rat    75 PIQTPSVCSDSLESPDEDIGSDSDVTTESGSSPSHSPEERQDSGSAPSPLSLLHSGVAS------ 133

  Fly   236 PKTPTMSEEKLTTRITAAQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENC 300
             |....||::                 ::|.:..|||.|.||||||||.|||||||||.|.|.:|
  Rat   134 -KGKHASEKR-----------------HKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDC 180

  Fly   301 DKRFSRSDELSRHKRTHTGEKKFQCSVCQKKFMRSDHLSKHVKRHNKDKANGVNR 355
            .|:|||||||:||.|||||||:|:|.:|:|:|||||||:||.:||.:...:.:.|
  Rat   181 LKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRHTEFHPSMIKR 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cbt	NP_722636.1	zf-C2H2	263..287	CDD:278523	14/23 (61%)
		C2H2 Zn finger	265..287	CDD:275368	14/21 (67%)
		COG5048	<270..362	CDD:227381	57/86 (66%)
		zf-H2C2_2	279..306	CDD:290200	19/26 (73%)
		C2H2 Zn finger	295..317	CDD:275368	14/21 (67%)
		zf-H2C2_2	309..332	CDD:290200	15/22 (68%)
		zf-C2H2	323..345	CDD:278523	13/21 (62%)
		C2H2 Zn finger	325..345	CDD:275368	12/19 (63%)
Klf9	NP_476559.2	KLF9_N	3..144	CDD:409239	18/92 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..51
		COG5048	<78..234	CDD:227381	73/179 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..143		15/87 (17%)
		C2H2 Zn finger	145..167	CDD:275368	14/21 (67%)
		C2H2 Zn finger	175..197	CDD:275368	14/21 (67%)
		C2H2 Zn finger	205..225	CDD:275368	12/19 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910