DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shv and DNAJC5

DIOPT Version :9

Sequence 1:	NP_608525.1	Gene:	shv / 33220	FlyBaseID:	FBgn0031256	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_079495.1	Gene:	DNAJC5 / 80331	HGNCID:	16235	Length:	198	Species:	Homo sapiens

Alignment Length:	174	Identity:	52/174 - (29%)
Similarity:	85/174 - (48%)	Gaps:	32/174 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SFAGRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNPDKRK 84
            |.:|...|.:|.:.|||.::::||:||:||.:.|||||.|:|:|:.||:::..|:.:|::..||.
Human    10 STSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRN 74

  Fly    85 TYDRCGE------ECLKKEGMMDHGGDPFSSFFGDFGFHFGG------------------DGQ-Q 124
            .||:.|.      |...:|.:..:  ...||::....|.|.|                  .|: :
Human    75 IYDKYGSLGLYVAEQFGEENVNTY--FVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCK 137

  Fly   125 QDAPRGADIVMDLYVSLEEL---YSGNFVEIVRNKPVTKPASGT 165
            ..||.|.:  .:.|||.|:|   ...:..|......|.:|||.|
Human   138 PKAPEGEE--TEFYVSPEDLEAQLQSDEREATDTPIVIQPASAT 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shv	NP_608525.1	DnaJ	22..346	CDD:223560	51/172 (30%)
		DnaJ	25..87	CDD:278647	25/61 (41%)
		DnaJ_C	131..328	CDD:199909	11/38 (29%)
		DnaJ_zf	160..>195	CDD:304418	4/6 (67%)
DNAJC5	NP_079495.1	DnaJ	15..>84	CDD:223560	28/68 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910